SCHEMBL7923865

SCHEMBL7923865

CC(=O)C(c1cccc(C(C(C)=O)N2C(=O)CCC2=O)c1)N1C(=O)CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
PKM P14618 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
SLC1A2 P43004 2/20 0.37
KMT2A Q03164 3/20 0.36
ATM Q13315 1/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C19 P33261 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
GLA P06280 1/20 0.33
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933681 0.74 ALDH1A1 (0.42) ALDH1A1PKMTRPV1CYP2D6CYP2C9
SCHEMBL9632134 0.73 LMNA (0.53) ALDH1A1PKMTRPV1CYP2D6SLC1A2
SCHEMBL7923888 0.71 ALDH1A1 (0.39) ALDH1A1PKMTRPV1SLC1A2KMT2A
SCHEMBL7933688 0.71 ALDH1A1 (0.39) ALDH1A1PKMTRPV1SLC1A2KMT2A
SCHEMBL7932066 0.71 ALDH1A1 (0.39) ALDH1A1PKMTRPV1SLC1A2KMT2A
SCHEMBL22207807 0.70 ALDH1A1 (0.46) ALDH1A1PKMTRPV1CYP2D6SLC1A2
SCHEMBL7923891 0.69 L3MBTL1 (0.35) ALDH1A1PKMTRPV1SLC1A2KMT2A
SCHEMBL6319092 0.69 LMNA (0.52) ALDH1A1PKMTRPV1SLC1A2KMT2A
SCHEMBL7933708 0.69 ALDH1A1 (0.45) ALDH1A1PKMTRPV1SLC1A2KMT2A
SCHEMBL23904643 0.68 CYP3A4 (0.60) ALDH1A1PKMKMT2ACYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0800551-B1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL NV (NL) 2001-06-13 EP disclosed
US-5844049-A Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds AKZO NOBEL NV (NL) 1998-12-01 US disclosed
EP-0800551-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS Akzo Nobel N.V. (NL) 1997-10-15 EP disclosed
WO-1996020246-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL N.V. (NL) 1996-07-04 WO disclosed