Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923865 | 0.69 | ALDH1A1 (0.41) | ALDH1A1PKMSLC1A2TRPV1CA1 | |
| SCHEMBL9632134 | 0.64 | LMNA (0.53) | ALDH1A1PKMSLC1A2TRPV1LMNA | |
| SCHEMBL2304471 | 0.63 | ALDH1A1 (1.00) | ALDH1A1PKMSLC1A2LMNAHDAC3 | |
| SCHEMBL1563867 | 0.63 | ALDH1A1 (1.00) | ALDH1A1PKMSLC1A2LMNAHDAC3 | |
| SCHEMBL7923860 | 0.63 | ALDH1A1 (0.42) | ALDH1A1PKMLMNAKMT2AGAA | |
| SCHEMBL7933681 | 0.62 | ALDH1A1 (0.42) | ALDH1A1PKMSLC1A2TRPV1CA1 | |
| SCHEMBL22207807 | 0.61 | ALDH1A1 (0.46) | ALDH1A1PKMSLC1A2TRPV1LMNA | |
| SCHEMBL8728754 | 0.61 | CYP2C19 (0.47) | PKMCA12CA9LMNA | |
| SCHEMBL6319092 | 0.60 | LMNA (0.52) | ALDH1A1PKMSLC1A2TRPV1LMNA | |
| SCHEMBL19621059 | 0.60 | ALDH1A1 (0.61) | ALDH1A1PKMSLC1A2LMNAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800551-B1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL NV (NL) | 2001-06-13 | — | — | EP | claimed |
| US-5844049-A | Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds | AKZO NOBEL NV (NL) | 1998-12-01 | — | — | US | claimed |
| EP-0800551-A1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | Akzo Nobel N.V. (NL) | 1997-10-15 | — | — | EP | claimed |
| WO-1996020246-A1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL N.V. (NL) | 1996-07-04 | — | — | WO | claimed |
| EP-0800551-B1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL NV (NL) | 2001-06-13 | — | — | EP | disclosed |
| US-5844049-A | Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds | AKZO NOBEL NV (NL) | 1998-12-01 | — | — | US | disclosed |
| EP-0800551-A1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | Akzo Nobel N.V. (NL) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020246-A1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL N.V. (NL) | 1996-07-04 | — | — | WO | disclosed |