Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 5/20 | 0.49 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637955 | 0.87 | NR1H4 (0.50) | TP53TSHRACACBEBPSIGMAR1 | |
| SCHEMBL29906526 | 0.81 | ACACB (0.45) | ACACB | |
| SCHEMBL15134804 | 0.80 | NPC1 (0.41) | EPHX1TRPV1DPP4 | |
| SCHEMBL15160674 | 0.80 | NPC1 (0.41) | EPHX1TRPV1DPP4 | |
| SCHEMBL13235780 | 0.80 | ALDH1A1 (0.55) | SIGMAR1 | |
| SCHEMBL20208030 | 0.80 | ALDH1A1 (0.55) | SIGMAR1 | |
| SCHEMBL10879579 | 0.77 | TP53 (0.53) | TP53TSHRACACBEBPSIGMAR1 | |
| SCHEMBL13235832 | 0.76 | TP53 (0.56) | TP53TSHRACACBEPHX1REN | |
| SCHEMBL7120642 | 0.76 | TP53 (0.51) | TP53TSHRACACBEBPSIGMAR1 | |
| SCHEMBL8967452 | 0.75 | TSHR (0.55) | TP53TSHRACACBEBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303823-B2 | ?CROSSED ALDOL CONDENSATION? OF A KETONE WITH AN ALDEHYDE IN THE PRESENCE OF A CATALYST SYSTEM CONSISTING OF DIMETHYLAMINE OR PYRROLIDINE AND A CARBOXYLIC ACID TO FORM AN ALPHA,BETA-UNSATURATED KETONE | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-16 | — | — | US | disclosed |
| US-20010003784-A1 | Process for preparing ketones, in particular 6-methylheptan-2-one | BASF AKTIENGESELLSCAFT (DE) | 2001-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003784-A1 | Process for preparing ketones, in particular 6-methylheptan-2-one | ADH1A, ADH1C, ADH5 | TP53 4861/4885TSHR 3537/4885ACACB 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.