Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3624389 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3623198 | 0.94 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL21142107 | 0.93 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3624599 | 0.92 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10406971 | 0.92 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3622120 | 0.92 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3627361 | 0.91 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3622865 | 0.89 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL15508203 | 0.89 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL24542207 | 0.88 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809566-B2 | Organocatalytic process for asymmetric synthesis of decanolides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-11-07 | — | — | US | disclosed |
| US-9765048-B2 | Organocatalytic process for asymmetric synthesis of decanolides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-09-19 | — | — | US | disclosed |
| US-20160272608-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-09-22 | — | — | US | disclosed |
| US-20160272609-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-09-22 | — | — | US | disclosed |
| US-9422230-B2 | Process for the preparation of an anticonvulsant agent pregabalin hydrochloride | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-08-23 | — | — | US | disclosed |
| US-20160229876-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2016-08-11 | — | — | US | disclosed |
| US-20160122289-A1 | PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-05 | — | — | US | disclosed |
| WO-2014037964-A2 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | WO | disclosed |
| US-20130184313-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-07-18 | — | — | US | disclosed |
| US-8445684-B2 | Nicotinic acetylcholine receptor ligands and the uses thereof | PsycoGenics Inc. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20100152450-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | PSYCHOGENICS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2010045212-A2 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | PSYCHOGENICS, INCSTATUTS (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272609-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | CDC14A, CDC14B, DDOST | SMN1; SMN2 4744/4885ALDH1A1 538/4885TDP1 3719/4885 |
| US-20100152450-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | CHRNG, CHRNA5, CHRNA2 | SMN1; SMN2 3245/4885ALDH1A1 1052/4885TDP1 2710/4885 |
| US-20160272608-A1 | ORGANOCATALYTIC PROCESS FOR ASYMMETRIC SYNTHESIS OF DECANOLIDES | CDC14A, CDC14B, DDOST | SMN1; SMN2 4744/4885ALDH1A1 538/4885TDP1 3719/4885 |
| US-20160122289-A1 | PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE | GABRE, GABRG1, GABRB2 | SMN1; SMN2 1798/4885ALDH1A1 961/4885TDP1 4106/4885 |
| US-20160229876-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE | MCL1, TP53, MMP8 | SMN1; SMN2 233/4885ALDH1A1 1551/4885TDP1 874/4885 |
| US-20130184313-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | CHRNG, CHRNA5, CHRNA2 | SMN1; SMN2 3245/4885ALDH1A1 1052/4885TDP1 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.