SCHEMBL19137754

SCHEMBL19137754

O=c1ccn(NC[C@H](O)[C@H](O)[C@H](O)CO)c(=O)[nH]1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
CRBN Q96SW2 3/20 0.34
POLB P06746 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PNP P00491 1/20 0.33
PKM P14618 1/20 0.33
SLC28A1 O00337 1/20 0.32
SLC28A2 O43868 1/20 0.32
SLC29A1 Q99808 1/20 0.32
SLC28A3 Q9HAS3 1/20 0.32
DDB1 Q16531 1/20 0.32
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916345 0.81 ENPP1 (0.37) DUT
SCHEMBL5683256 0.79 LMNA (0.35) DUTALDH1A1LMNACRBNPOLB
SCHEMBL5604080 0.77 PKM (0.40) DUTALDH1A1LMNACRBNPKM
SCHEMBL11389897 0.67 CRBN (0.46) DUTALDH1A1LMNACRBNPKM
SCHEMBL23171170 0.65 POLB (0.44) DUTALDH1A1LMNACRBNPOLB
SCHEMBL7926412 0.65 PKM (0.40) DUTALDH1A1LMNACRBNPKM
SCHEMBL10196375 0.64 PKM (0.46) DUTALDH1A1LMNAPKM
SCHEMBL2181554 0.63 CRBN (0.54) DUTALDH1A1LMNACRBNPKM
SCHEMBL9019445 0.63 CRBN (0.44) DUTALDH1A1LMNACRBNDDB1
SCHEMBL14237174 0.63 POLB (0.45) DUTALDH1A1LMNACRBNPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10245262-B2 Immunological reagents and uses therefor THE UNIVERSITY OF QUEENSLAND (AU) 2019-04-02 US claimed
US-20170209442-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR MONASH UNIVERSITY (AU) 2017-07-27 US claimed
US-20230028742-A1 COMPOSITIONS AND USES THEREOF UNIV MELBOURNE (AU) 2023-01-26 US disclosed
US-10245262-B2 Immunological reagents and uses therefor THE UNIVERSITY OF QUEENSLAND (AU) 2019-04-02 US disclosed
US-20170209442-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR MONASH UNIVERSITY (AU) 2017-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10245262-B2 Immunological reagents and uses therefor CD81, MRGPRX2, MRGPRX1 DUT 3138/4885ALDH1A1 999/4885LMNA 3983/4885
US-20170209442-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR CD81, MRGPRX2, MRGPRX1 DUT 3138/4885ALDH1A1 999/4885LMNA 3983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.