SCHEMBL7929792

SCHEMBL7929792

O=C1c2ccc(Nc3ccccc3[N+](=O)[O-])cc2C(=O)c2c(O)ccc(O)c21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.57
TDP1 Q9NUW8 5/20 0.57
MAPK1 P28482 4/20 0.57
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
POLB P06746 3/20 0.57
GAA P10253 2/20 0.57
APEX1 P27695 1/20 0.57
CASP6 P55212 1/20 0.57
PKM P14618 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.51
ALDH1A1 P00352 2/20 0.51
CASP7 P55210 1/20 0.51
TSHR P16473 4/20 0.48
CYP1A2 P05177 3/20 0.48
CYP3A4 P08684 3/20 0.48
HIF1A Q16665 3/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2D6 P10635 1/20 0.48
LMNA P02545 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929854 0.82 POLB (0.50) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL7930693 0.79 CASP6 (0.48) MAPTMEN1KMT2APOLBAPEX1
SCHEMBL7928287 0.79 P2RY2 (0.48) MAPTMAPK1MEN1KMT2APOLB
SCHEMBL7930873 0.77 MEN1 (0.56) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL7921433 0.76 MEN1 (0.45) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL7927191 0.76 EGFR (0.51) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL7930683 0.75 CYP3A4 (0.56) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL11506844 0.74 ALDH1A1 (0.89) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL7930479 0.73 CYP3A4 (0.54) MAPTTDP1MAPK1MEN1KMT2A
SCHEMBL109703 0.73 MAPT (1.00) MAPTTDP1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed