Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.65 |
| ▸ | TUBB | P07437 | 2/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.65 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514379 | 0.78 | TAS1R3 (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16248327 | 0.75 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3991708 | 0.74 | NAE1 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7023745 | 0.72 | TAS1R3 (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14121638 | 0.71 | PPARG (0.56) | TAS1R3TAS1R1CTNNB1WNT3AMAOB | |
| SCHEMBL4438920 | 0.71 | MAOA (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL103794 | 0.71 | TUBB4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29377304 | 0.71 | TUBB4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL701044 | 0.71 | TAS1R3 (1.00) | TAS1R3TAS1R1 | |
| SCHEMBL701043 | 0.71 | TAS1R3 (1.00) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |