SCHEMBL7928568

SCHEMBL7928568

C=CCc1cc[c]c(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
ALDH1A1 P00352 2/20 0.32
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5454296 0.76 GABRA1 (0.41) GABRA1GABRB2ALDH1A1PPARGPPARD
SCHEMBL4371459 0.74 THRB (0.33) MEN1KMT2A
SCHEMBL8059533 0.74 MEN1 (0.35) GABRA1GABRB2ALDH1A1MEN1KMT2A
SCHEMBL486931 0.74 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL22355711 0.72 GABRA1 (0.54) GABRA1GABRB2ALDH1A1MEN1KMT2A
SCHEMBL4551393 0.70 GABRA1 (0.40) GABRA1GABRB2ALDH1A1CYP3A4ALOX15
SCHEMBL7854186 0.69 SRD5A1 (0.38) GABRA1GABRB2ALDH1A1PPARGPPARD
SCHEMBL11759870 0.68 GABRA1 (0.36) GABRA1GABRB2ALDH1A1PPARGPPARD
SCHEMBL2968255 0.68 TYR (0.37) MEN1KMT2ATP53CYP3A4ALOX15
SCHEMBL723360 0.68 GABRA1 (0.33) GABRA1GABRB2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277925-B1 COMPRISING A CURABLE POLYMER, AN ORGANIC PEROXIDE INITIATOR, AND AN ALLYL COMPOUND AS SCORCH RETARDER HERCULES INCORPORATED 2001-08-21 US disclosed