Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889001 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2MAPT | |
| SCHEMBL393930 | 0.78 | GABRA1 (0.40) | GABRA1GABRB2MAPT | |
| SCHEMBL4790115 | 0.78 | IMPDH2 (0.33) | GABRA1GABRB2 | |
| SCHEMBL299415 | 0.78 | SRD5A1 (0.39) | GABRA1GABRB2CYP3A4MAPT | |
| SCHEMBL15824281 | 0.78 | GABRA1 (0.41) | GABRA1GABRB2 | |
| SCHEMBL8623061 | 0.74 | — | — | |
| SCHEMBL176260 | 0.73 | GABRA1 (0.42) | GABRA1GABRB2MAPT | |
| SCHEMBL10715540 | 0.73 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL8677546 | 0.73 | AURKA (0.35) | GABRA1GABRB2MAPT | |
| SCHEMBL3410411 | 0.73 | ADRB2 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180264448-A1 | NI(0) CATALYSTS | NATIONAL SCIENCE FOUNDATION | 2018-09-20 | — | — | US | claimed |
| EP-2327748-B1 | Water-based ink for ink-jet recording, ink cartridge, and ink-jet recording apparatus | BROTHER IND LTD (JP) | 2012-03-21 | — | — | EP | claimed |
| US-20090253799-A1 | DIVALENT HYDRAZIDE COMPOUND CONJUGATES FOR INHIBITING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-10-08 | — | — | US | claimed |
| US-20080177108-A1 | Phenyloxyaniline derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | US | claimed |
| US-6462034-B1 | MULTIBINDING COMPOUNDS CONTAINING A SYMETRICAL DIAMINOTETRA-ETHERDODECANE RING WITH TWO SECONDARY AMIDE AND ADDITIONAL SUBSTITUENTS; VOLTAGE GATED SODIUM CHANNEL MODULATORS; LONG DURATION | THERAVANCE, INC. | 2002-10-08 | — | — | US | claimed |
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | claimed |
| US-5308600-A | Polyether emulsifier | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-03 | — | — | US | claimed |
| EP-0376138-B1 | Copolymers, their mixtures with polymers of esters of (meth)acrylic acid, and their use in improving the flowability of crude oil at a low temperature | HOECHST AG (DE) | 1994-01-19 | — | — | EP | claimed |
| EP-0376138-A2 | Copolymers, their mixtures with polymers of esters of (meth)acrylic acid, and their use in improving the flowability of crude oil at a low temperature | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-04 | — | — | EP | claimed |
| US-4885392-A | Derivatives of 1,3-bissubstituted 2-propanol containing amino groups, methods for their preparation and their use | HOECHST AG (DE) | 1989-12-05 | — | — | US | claimed |
| US-4769167-A | Aqueous functional fluids based on polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-06 | — | — | US | claimed |
| EP-0141321-B1 | ORGANIC SILICON COMPOUNDS AND TEXTILE FIBRE PREPARATIONS CONTAINING THEM | Th. Goldschmidt AG (DE) | 1988-06-01 | — | — | EP | claimed |
| EP-0121230-B1 | COPOLYMERS CONTAINING ESTERS OF CROTONIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS THICKENERS IN AQUEOUS SYSTEMS AND IN DRESSINGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-01-07 | — | — | EP | claimed |
| US-4569965-A | Crotonate-containing copolymers, processes for their preparation and their use as thickeners in aqueous systems and as sizing agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-11 | — | — | US | claimed |
| JP-6049153-A | — | — | None | — | — | JP | disclosed |
| CN-114409602-B | Method for synthesizing alpha-keto acid by using oxalyl chloride and Grignard reagent as raw materials | 武汉大学 | 2024-01-30 | — | — | CN | disclosed |
| EP-2433987-B1 | COMPOSITION FOR PREPARING EMULSION OR MICROEMULSION FORMULATIONS | NIPPON SODA CO (JP) | 2016-06-29 | — | — | EP | disclosed |
| EP-0025850-A2 | Process for the polymerization of cyclic polyhalophosphazenes using a catalyst composition of boron trihalide and oxygenated phosphorus compounds | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-04-01 | — | — | EP | disclosed |
| US-4226840-A | Process for the polymerization of cyclic polyhalophosphazenes using a catalyst composition of boron trihalide and oxygenated phosphorus compounds | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0014772-A1 | Process for the preparation of powdery coating compositions based on polyamides containing at least 10 aliphatically bound carbon atoms for each carbonamide group | CHEMISCHE WERKE HÜLS AG (DE) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253799-A1 | DIVALENT HYDRAZIDE COMPOUND CONJUGATES FOR INHIBITING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SLC26A4, SLC26A3 | GABRA1 1738/4885GABRB2 1196/4885CYP1A2 4859/4885 |
| US-20180264448-A1 | NI(0) CATALYSTS | SOD1, SCO2, CNOT9 | GABRA1 4575/4885GABRB2 4148/4885CYP1A2 2880/4885 |
| US-20080177108-A1 | Phenyloxyaniline derivatives | PNMT, PAH, NAT1 | GABRA1 1224/4885GABRB2 1078/4885CYP1A2 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.