Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 7/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | PTGES | O14684 | 6/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928277 | 0.89 | MMP12 (0.64) | MMP12MMP13MMP3MMP2FFAR1 | |
| SCHEMBL3467249 | 0.88 | MMP12 (0.54) | MMP12MMP13MMP3MMP2FFAR1 | |
| SCHEMBL7932591 | 0.88 | MMP12 (0.63) | MMP12MMP13MMP3MMP2FFAR1 | |
| SCHEMBL8041180 | 0.82 | PPARG (0.61) | MMP3MMP2PTGESALOX5PPARG | |
| SCHEMBL3467000 | 0.81 | MMP12 (0.51) | MMP12MMP13MMP3MMP2FFAR1 | |
| SCHEMBL3467017 | 0.81 | MMP12 (0.57) | MMP12MMP13MMP3MMP2FFAR1 | |
| SCHEMBL3466325 | 0.79 | FFAR1 (0.57) | MMP12MMP13FFAR1FFAR4FOLH1 | |
| SCHEMBL7917889 | 0.79 | MMP12 (0.55) | MMP12MMP13MMP3MMP2FFAR1 | |
| SCHEMBL7924636 | 0.79 | MMP12 (0.65) | MMP12MMP13MMP2FFAR1FFAR4 | |
| SCHEMBL1858749 | 0.79 | FOLH1 (0.50) | MMP12MMP13MMP3MMP2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |