SCHEMBL792902

SCHEMBL792902

Oc1cccc2c1N=N[N]2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
CA2 P00918 3/20 0.36
HPGD P15428 3/20 0.36
ALOX15 P16050 3/20 0.36
RECQL P46063 3/20 0.36
HSD17B10 Q99714 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
EGFR P00533 2/20 0.36
LMNA P02545 2/20 0.36
FYN P06241 2/20 0.36
MMP9 P14780 2/20 0.36
MMP2 P08253 2/20 0.36
CA1 P00915 2/20 0.36
ADAMTS4 O75173 1/20 0.36
MMP8 P22894 1/20 0.36
CA6 P23280 1/20 0.36
CDK2 P24941 1/20 0.36
MMP12 P39900 1/20 0.36
ADAMTS5 Q9UNA0 1/20 0.36
MAPT P10636 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2264409 0.73 CYP2A6 (0.35) ALDH1A1CA2CA1ACHETSHR
SCHEMBL10588380 0.73
SCHEMBL5600028 0.67 PDK2 (0.33)
SCHEMBL5603693 0.66 GRM5 (0.33) ALDH1A1HPGDGAAKDM4E
SCHEMBL1491322 0.64 ALDH1A1 (0.36) ALDH1A1CA2HPGDALOX15RECQL
SCHEMBL5602255 0.63 NOS1 (0.39) POLB
Water SCHEMBL20742739 0.62 MAPT (0.33) MAPT
SCHEMBL9624840 0.61 MAOA (0.48) ALDH1A1CA2HPGDALOX15RECQL
SCHEMBL11880716 0.57
SCHEMBL172721 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3964067-B1 COMPOSITION COMPRISING A MOLECULE HAVING PESTICIDAL UTILITY DOW AGROSCIENCES LLC (US) 2024-01-03 EP disclosed
EP-3971166-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2022-03-23 EP disclosed
EP-3964495-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2022-03-09 EP disclosed
EP-3526192-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-11-17 EP disclosed
EP-3407717-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-07-28 EP disclosed
EP-3407718-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-02-17 EP disclosed
EP-3526192-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2019-08-21 EP disclosed
US-10308610-B2 Inhibitor compounds of phosphodiesterase type 10A AbbVie Deutschland GmbH & Co. KG (DE) 2019-06-04 US disclosed
US-10206401-B2 Pyridine compounds for controlling invertebrate pests II BASF SE (DE) 2019-02-19 US disclosed
US-20180116221-A1 Pyridine Compounds for Controlling Invertebrate Pests II BASF SE (DE) 2018-05-03 US disclosed
WO-2011117804-A1 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-09-29 WO disclosed
WO-2011117213-A1 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-09-29 WO disclosed
WO-2011117198-A2 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-09-29 WO disclosed
WO-2011117806-A2 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-09-29 WO disclosed
WO-2011009804-A2 PYRIDINE DERIVATIVES COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-01-27 WO disclosed
WO-2011003796-A1 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-01-13 WO disclosed
WO-2011003793-A1 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-01-13 WO disclosed
EP-1699763-A1 3-TRIFLUOROMETHYL PICOLINIC ACID ANILIDES, AND USE THEREOF AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 2006-09-13 EP disclosed
WO-2005063710-A1 3-TRIFLUOROMETHYL PICOLINIC ACID ANILIDES, AND USE THEREOF AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 WO disclosed
WO-1998000434-A1 MODIFIED OLIGONUCLEOTIDES NOVARTIS AG (CH) 1998-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10206401-B2 Pyridine compounds for controlling invertebrate pests II PRXL2A, NR2C2, SHROOM3 ALDH1A1 1345/4885CA2 793/4885HPGD 2559/4885
US-20180116221-A1 Pyridine Compounds for Controlling Invertebrate Pests II PRXL2A, SHROOM3, NR2C2 ALDH1A1 1331/4885CA2 726/4885HPGD 2415/4885
US-10308610-B2 Inhibitor compounds of phosphodiesterase type 10A PDE3A, PDE5A, PDE3B ALDH1A1 1036/4885CA2 301/4885HPGD 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.