Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 7/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493734 | 0.89 | CETP (0.40) | FDFT1LPAR1LPAR5 | |
| SCHEMBL407786 | 0.87 | LTA4H (0.41) | FDFT1 | |
| SCHEMBL7934903 | 0.84 | TTR (0.41) | FDFT1 | |
| SCHEMBL7931643 | 0.84 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL9561225 | 0.83 | PPARA (0.37) | — | |
| SCHEMBL7922569 | 0.83 | FDFT1 (0.40) | FDFT1 | |
| SCHEMBL9570834 | 0.83 | TACR1 (0.34) | LPAR1LPAR5POLB | |
| SCHEMBL7932383 | 0.83 | FDFT1 (0.37) | FDFT1 | |
| SCHEMBL9628951 | 0.82 | MAOA (0.39) | — | |
| SCHEMBL9629106 | 0.81 | FDFT1 (0.35) | FDFT1LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |