Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620118 | 0.87 | ALDH1A1 (0.41) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL22874628 | 0.83 | CES2 (0.56) | CES2CES1CA1CA2BCL2L1 | |
| SCHEMBL29043915 | 0.82 | CES2 (0.50) | CES2CES1CA1CA2BCL2L1 | |
| SCHEMBL10348275 | 0.80 | RXRA (0.40) | CES1BCL2L1BADPTPN1NPC1 | |
| SCHEMBL6522491 | 0.78 | CES2 (0.71) | CES2CES1CA1CA2BCL2L1 | |
| SCHEMBL16823 | 0.78 | CES1 (0.62) | CES2CES1CA1CA2BCL2L1 | |
| SCHEMBL7532519 | 0.78 | MAPT (0.52) | CES2CA1CA2PTPN1NPC1 | |
| SCHEMBL8648902 | 0.78 | CES2 (0.56) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL8386482 | 0.78 | CES2 (0.71) | CES2CES1CA1CA2BCL2L1 | |
| SCHEMBL1716676 | 0.77 | CES1 (0.45) | CES2CES1CA1CA2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11570987-B2 | Pesticidal compounds and methods of use | NEW YORK UNIVERSITY (US) | 2023-02-07 | — | — | US | disclosed |
| US-11570987-B2 | Pesticidal compounds and methods of use | NEW YORK UNIVERSITY (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210092950-A1 | PESTICIDAL COMPOUNDS AND METHODS OF USE | NEW YORK UNIVERSITY (US) | 2021-04-01 | — | — | US | disclosed |
| US-20210092950-A1 | PESTICIDAL COMPOUNDS AND METHODS OF USE | NEW YORK UNIVERSITY (US) | 2021-04-01 | — | — | US | disclosed |
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210092950-A1 | PESTICIDAL COMPOUNDS AND METHODS OF USE | ACHE, DDT, PTMS | CES2 475/4885CES1 1295/4885CA1 755/4885 |
| US-11570987-B2 | Pesticidal compounds and methods of use | ACHE, DDT, PTMS | CES2 475/4885CES1 1295/4885CA1 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.