SCHEMBL7929162

SCHEMBL7929162

O=[N+]([O-])c1ccc([S+]([O-])c2ccc(F)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPB1 P04792 4/20 0.58
POLB P06746 1/20 0.53
KCNJ1 P48048 1/20 0.46
KCNH2 Q12809 1/20 0.46
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
ALDH1A1 P00352 5/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 3/20 0.44
ALOX12 P18054 2/20 0.44
GAA P10253 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 2/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ACHE P22303 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576857 0.89 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ALMNATDP1
SCHEMBL7026994 0.85 HSPB1 (0.75) HSPB1POLBKCNJ1KCNH2MAOA
SCHEMBL536 0.85 HSPB1 (0.75) HSPB1POLBKCNJ1KCNH2MAOA
Fluoride SCHEMBL4551988 0.83 HSPB1 (0.72) HSPB1POLBKCNJ1KCNH2MAOA
SCHEMBL28001935 0.83 HSPB1 (0.72) HSPB1POLBKCNJ1KCNH2MAOA
Water SCHEMBL28147677 0.83 HSPB1 (0.72) HSPB1POLBKCNJ1KCNH2MAOA
Fluoride SCHEMBL4551986 0.83 HSPB1 (0.72) HSPB1POLBKCNJ1KCNH2MAOA
SCHEMBL2816722 0.82 ALDH1A1 (0.60) POLBALDH1A1MEN1KMT2ALMNA
Ethane SCHEMBL28251595 0.81 HSPB1 (0.69) HSPB1POLBKCNJ1KCNH2MAOA
Ethylene SCHEMBL27864908 0.81 HSPB1 (0.69) HSPB1POLBKCNJ1KCNH2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed