Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995832 | 0.84 | HSD17B2 (0.41) | HSD17B1HSD17B2DHODHHDAC2CNR1 | |
| SCHEMBL11422284 | 0.81 | GAA (0.45) | GAATDP1MAPT | |
| SCHEMBL15453207 | 0.75 | HSD17B1 (0.40) | HSD17B1HSD17B2DHODHMAPTPTPN5 | |
| SCHEMBL21390859 | 0.72 | TSPO (0.44) | HSD17B1HSD17B2HDAC2HPGDMAPT | |
| SCHEMBL13241986 | 0.72 | HSD17B1 (0.40) | HSD17B1HSD17B2CNR1HPGDPPARG | |
| SCHEMBL8420682 | 0.72 | FSCN1 (0.50) | HSD17B1HSD17B2TDP1MAPTMCL1 | |
| SCHEMBL272091 | 0.71 | RXRB (0.57) | HSD17B1HSD17B2DHODHAKR1C2AKR1C1 | |
| SCHEMBL4428711 | 0.70 | MAPT (0.64) | HSD17B1HSD17B2GAADHODHHDAC2 | |
| SCHEMBL28990134 | 0.70 | MCL1 (0.45) | GAAHDAC2MAPTLMNAMCL1 | |
| SCHEMBL6561397 | 0.70 | ACHE (0.61) | HSD17B1HSD17B2HPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228547-B1 | CHARGE TRANSFER COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-05-08 | — | — | US | disclosed |