Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928552 | 0.86 | SLC2A1 (0.44) | CSNK1ESLC2A1SPHK1SPHK2S1PR2 | |
| Hydrochloric Acid SCHEMBL7934412 | 0.85 | SPHK1 (0.50) | SPHK1SPHK2S1PR2S1PR1S1PR3 | |
| SCHEMBL10495610 | 0.73 | PSMD14 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL8501636 | 0.72 | SPHK1 (0.50) | SPHK1SPHK2S1PR2S1PR1S1PR3 | |
| SCHEMBL7932000 | 0.72 | SPHK1 (0.58) | CSNK1ESPHK1S1PR2S1PR1S1PR3 | |
| SCHEMBL8503490 | 0.72 | SPHK1 (0.50) | SPHK1SPHK2S1PR2S1PR1S1PR3 | |
| SCHEMBL8501713 | 0.72 | SPHK1 (0.50) | SPHK1SPHK2S1PR2S1PR1S1PR3 | |
| SCHEMBL10497065 | 0.72 | CSNK1E (0.66) | CSNK1EMMP2 | |
| SCHEMBL1168932 | 0.72 | CSNK1E (0.66) | CSNK1EMMP2 | |
| SCHEMBL10497215 | 0.72 | CSNK1E (0.66) | CSNK1EMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284915-B2 | Process for preparing 2-amino malonic acid derivatives and 2-amino-1,3-propanediol derivatives, and intermediates for preparing the same | TAITO CO., LTD (JP) | 2001-09-04 | — | — | US | disclosed |
| US-20010008945-A1 | PROCESS FOR PREPARING 2-AMINO MALONIC ACID DERIVATIVES AND 2-AMINO-1,3 - PROPANEDIOL DERIVATIVES, AND INTERMEDIATES FOR PREPARING THE SAME | MITSUBISHI PHARMA CORPORATION (JP) | 2001-07-19 | — | — | US | disclosed |
| EP-0989113-A1 | PROCESSES FOR PRODUCING 2-AMINOMALONIC ACID DERIVATIVES AND 2-AMINO-1,3-PROPANEDIOL DERIVATIVES, AND INTERMEDIATES FOR PRODUCING THE DERIVATIVES | TAITO CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008945-A1 | PROCESS FOR PREPARING 2-AMINO MALONIC ACID DERIVATIVES AND 2-AMINO-1,3 - PROPANEDIOL DERIVATIVES, AND INTERMEDIATES FOR PREPARING THE SAME | BCAT2, BCAT1, BCKDK | CSNK1E 2415/4885SLC2A1 675/4885SPHK1 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.