Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317124 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTT | |
| SCHEMBL1789913 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTT | |
| SCHEMBL5525306 | 0.83 | ALDH1A3 (0.37) | ALDH1A1 | |
| SCHEMBL7089384 | 0.81 | ALDH1A1 (0.39) | ALDH1A1GAALMNAHTT | |
| SCHEMBL7452976 | 0.81 | LTA4H (0.40) | ALDH1A1GAA | |
| SCHEMBL14763050 | 0.80 | PDE2A (0.41) | ALDH1A1GAA | |
| SCHEMBL7575011 | 0.80 | LMNA (0.39) | ALDH1A1LMNAHTT | |
| SCHEMBL16094149 | 0.80 | CYP19A1 (0.41) | ALDH1A1HTT | |
| SCHEMBL4671383 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAALMNAHTT | |
| SCHEMBL4811110 | 0.80 | KDM4E (0.38) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245922-B1 | PREPARED BY REACTING AN ELECTROPHILIC 2-ALKENYL AZALACTONE WITH A NUCLEOPHILIC AROMATIC KETONE; CAN BE COPOLYMERIZED WITH ACRYLIC MONOMERS AND PHOTOACTIVATED BY ACTINIC RADIATION TO CROSSLINK THE POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2001-06-12 | — | — | US | disclosed |
| EP-0837844-B1 | ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND | MINNESOTA MINING & MFG (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0837844-A1 | ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997005101-A1 | ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-02-13 | — | — | WO | disclosed |