SCHEMBL7933016

SCHEMBL7933016

COC(=O)N(c1ccccc1)c1c(F)c2c(c(F)c1N(C(=O)OC)c1ccccc1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.37
PIM1 P11309 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
MAOA P21397 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.35
NPSR1 Q6W5P4 3/20 0.34
NR3C2 P08235 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CHRM4 P08173 2/20 0.33
CHRM3 P20309 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928309 0.95 EGFR (0.35) EGFRPIM1ESR1ESR2MEN1
SCHEMBL3276086 0.73 L3MBTL1 (0.61) MEN1KMT2AMAPTL3MBTL1ATM
SCHEMBL2093371 0.72 MEN1 (0.43) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL29460885 0.68 ALDH1A1 (0.40) MEN1KMT2AMAPTL3MBTL1ATM
SCHEMBL2092944 0.67 PTGIR (0.52) L3MBTL1ATMTDP1
SCHEMBL7930883 0.66 CXCR2 (0.47) MEN1KMT2AMAPTMAOAL3MBTL1
SCHEMBL28111104 0.66 L3MBTL1 (0.47) MEN1KMT2AMAPTL3MBTL1ATM
Methyl Carbamate SCHEMBL11287154 0.66 L3MBTL1 (0.52) MEN1KMT2AMAPTL3MBTL1ATM
SCHEMBL497324 0.65 CSNK2A2 (0.54) EGFRPIM1ESR1MEN1KMT2A
SCHEMBL7933112 0.65 EGFR (0.51) EGFRPIM1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed