SCHEMBL7933153

SCHEMBL7933153

C[Ge](c1ccccc1)=[Hf](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7935464 0.84 HTR6 (0.31)
SCHEMBL4479589 0.83 HTR6 (0.33) SIGMAR1
SCHEMBL3383168 0.74 HTR2A (0.35) SIGMAR1MEN1KMT2A
SCHEMBL3383074 0.71 HTR6 (0.33) SIGMAR1
SCHEMBL7938649 0.71 LMNA (0.32)
SCHEMBL7951352 0.71 HTR2A (0.35) SIGMAR1
SCHEMBL215792 0.71 HTR2A (0.35)
SCHEMBL4470704 0.70 HTR6 (0.36) SIGMAR1
Hydrochloric Acid SCHEMBL7107339 0.70 KDM4E (0.33) SIGMAR1MEN1KMT2A
SCHEMBL217218 0.70 HTR6 (0.33) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed