SCHEMBL7933510

SCHEMBL7933510

COC(=O)c1ccc(CNC(C)=O)cc1S(N)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.52
CA1 P00915 3/20 0.52
CA5A P35218 1/20 0.52
CA9 Q16790 1/20 0.52
GAA P10253 2/20 0.43
CA7 P43166 2/20 0.42
CA14 Q9ULX7 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTT P42858 1/20 0.41
CA12 O43570 1/20 0.41
KMT2A Q03164 1/20 0.41
CDK1 P06493 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31357368 0.84 CA2 (0.52) CA2CA1CA5ACA9GAA
SCHEMBL5412365 0.84 CA2 (0.52) CA2CA1CA5ACA9GAA
SCHEMBL7935254 0.83 SMN1; SMN2 (0.40) CA2CA1CA5ACA9GAA
SCHEMBL29253953 0.83 CA2 (0.58) CA2CA1CA5ACA9GAA
SCHEMBL22010625 0.82 CA2 (0.56) CA2CA1CA5ACA9GAA
SCHEMBL14401631 0.81 SMN1; SMN2 (0.56) CA2CA1CA9GAACA7
SCHEMBL28483919 0.81 CA2 (0.55) CA2CA1CA5ACA9GAA
SCHEMBL21962935 0.80 CA2 (0.54) CA2CA1CA5ACA9GAA
SCHEMBL7727266 0.79 CA2 (0.50) CA2CA1CA5ACA9GAA
SCHEMBL30925089 0.77 CA2 (0.51) CA2CA1CA5ACA9GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9693558-B2 Process for preparing a novel crystalline form of mesosulfuron-methyl and use of the same ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-07-04 US disclosed
US-20170156330-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF MESOSULFURON-METHYL AND USE OF THE SAME ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-06-08 US disclosed
WO-2017092477-A1 PROCESS FOR PREPARING NOVEL CRYSTALLINE FORM OF MESOSULFURON-METHYL AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-06-08 WO disclosed
US-20170156332-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-06-08 US disclosed
US-9661851-B1 Synergistic herbicidal composition and use thereof ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-05-30 US disclosed
US-6239306-B1 Phenylsulfonylureas, processes for their preparation, and their use as herbicides and plant growth regulations HOECHST SCHERING AGREVO GMBH (DE) 2001-05-29 US disclosed
US-5925597-A PRE-EMERGENCE AND POST-EMERGENCE HERBICIDES HOECHST SCHERING AGREVO GMBH (DE) 1999-07-20 US disclosed
EP-0723534-B1 PHENYLSULFONYL UREAS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-07-29 EP disclosed
US-5648315-A Phenylsulfonylureas, Processes for their-preparation, and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1997-07-15 US disclosed
EP-0723534-A1 PHENYLSULFONYL UREAS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1996-07-31 EP disclosed
WO-1995010507-A1 PHENYLSULFONYL UREAS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170156330-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF MESOSULFURON-METHYL AND USE OF THE SAME MPST, STS, SCLY CA2 2254/4885CA1 891/4885CA5A 1985/4885
US-20170156332-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF DDT, AS3MT, METTL3 CA2 744/4885CA1 1097/4885CA5A 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.