Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.56 |
| ▸ | RXRB | P28702 | 3/20 | 0.56 |
| ▸ | RXRG | P48443 | 2/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | CD69 | Q07108 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717865 | 0.88 | RXRA (0.68) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL3811969 | 0.82 | RXRA (0.58) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL4494395 | 0.81 | RXRA (0.56) | RXRARXRBRXRGCA2CAMK2A | |
| SCHEMBL477986 | 0.80 | CA2 (0.58) | RXRACA2CAMK2AHSP90AB1THRA | |
| SCHEMBL29071552 | 0.79 | GABRA1 (0.50) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL7794784 | 0.77 | RXRA (0.52) | RXRARXRBRXRGCYP1A2CYP2C19 | |
| SCHEMBL5167852 | 0.76 | GABRA1 (0.62) | GABRA1GABRB2CYP2C19EGFR | |
| SCHEMBL12115600 | 0.76 | GABRA1 (0.62) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL3904523 | 0.75 | HCAR1 (0.50) | RXRACA2CAMK2AHSP90AB1THRA | |
| SCHEMBL3512676 | 0.75 | GABRA1 (0.60) | RXRARXRBRXRGGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0861847-A2 | Stabilizer composition and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |