SCHEMBL477986

SCHEMBL477986

O=C(O)Cc1cc(O)cc(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.58
CAMK2A Q9UQM7 1/20 0.58
HSP90AB1 P08238 1/20 0.56
GAA P10253 4/20 0.52
TSHR P16473 3/20 0.52
POLB P06746 2/20 0.52
LMNA P02545 2/20 0.52
NFKB1 P19838 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 2/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 2/20 0.52
RGS12 O14924 1/20 0.52
APEX1 P27695 1/20 0.52
THPO P40225 1/20 0.52
BLM P54132 1/20 0.52
GNAI1 P63096 1/20 0.52
PMP22 Q01453 1/20 0.52
HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334919 0.84 HCAR1 (0.50) CA2CAMK2AHSP90AB1GAATSHR
SCHEMBL585787 0.84 CA2 (0.48) CA2CAMK2AHSP90AB1GAATSHR
SCHEMBL585478 0.84 HCAR1 (0.50) CA2CAMK2AHSP90AB1GAATSHR
SCHEMBL3904523 0.84 HCAR1 (0.50) CA2CAMK2AHSP90AB1GAATSHR
SCHEMBL8862011 0.84 CA2 (0.48) CA2CAMK2AHSP90AB1GAATSHR
SCHEMBL583915 0.83 AKR1B1 (0.60) CA2CAMK2AGAATSHRPOLB
SCHEMBL28721957 0.81 HSP90AB1 (0.58) CA2CAMK2AHSP90AB1LMNAACHE
SCHEMBL29233492 0.80 HSP90AB1 (0.52) CA2CAMK2AHSP90AB1ACHECA12
SCHEMBL7933700 0.80 RXRA (0.56) CA2CAMK2AHSP90AB1THRBTHRA
SCHEMBL4494395 0.80 RXRA (0.56) CA2CAMK2ALMNATHRBRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836205-A Perovskite solar cell based on multifunctional additive and preparation method thereof 东方电气长三角(杭州)创新研究院有限公司 2025-04-15 CN claimed
US-12171856-B2 Use of salidroside derivative in external preparation for skin whitening shanghai Cheermore Biological Technology Co., Ltd (CN) 2024-12-24 US claimed
CN-117843276-B Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-11-26 CN claimed
CN-118755405-A Substrate-free double-sided adhesive material applied to FPC (Flexible printed Circuit) and preparation method thereof 安徽明讯新材料科技股份有限公司 2024-10-11 CN claimed
CN-117843276-A Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-04-09 CN claimed
CN-112250546-B Synthesis method of (E) -3, 5-dihydroxyl-4-isopropyl stilbene 中山大学 2023-05-12 CN claimed
CN-112390707-B Preparation and application of (Z) -3, 5-dihydroxy-4-isopropyl stilbene 中山大学 2023-04-28 CN claimed
EP-3915998-B1 APPLICATION OF SALIDROSIDE DERIVATIVE IN SKIN-WHITENING AGENT FOR EXTERNAL USE SHANGHAI CHEERMORE BIOLOGICAL TECH CO LTD (CN) 2023-01-18 EP claimed
CN-112716824-B Application of salidroside derivative in skin whitening external preparation 上海澄穆生物技术有限公司 2022-11-18 CN claimed
US-20220142895-A1 USE OF SALIDROSIDE DERIVATIVE IN EXTERNAL PREPARATION FOR SKIN WHITENING shanghai Cheermore Biological Technology Co., Ltd (CN) 2022-05-12 US claimed
US-20090088572-A1 METHOD FOR PREPARING LADDERANES NATIONAL SCIENCE FOUNDATION 2009-04-02 US claimed
WO-2007089785-A2 APPARATUS AND SEMICONDUCTOR CO-CRYSTAL UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2007-08-09 WO claimed
EP-1628621-A2 POLYMERIC CONJUGATES FOR TISSUE ACTIVATED DRUG DELIVERY Vectramed, Inc. (US) 2006-03-01 EP claimed
WO-2005035473-A2 METHOD FOR PREPARING LADDERANES FROM PRE-ORIENTED POLYENES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-04-21 WO claimed
WO-2004110358-A2 POLYMERIC CONJUGATES FOR TISSUE ACTIVATED DRUG DELIVERY VECTRAMED, INC. (US) 2004-12-23 WO claimed
US-20040228831-A1 Polymeric conjugates for tissue activated drug delivery VECTRAMED, INC. 2004-11-18 US claimed
JP-2002542304-A 2002-12-10 JP claimed
EP-1176985-A2 ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES Vectramed, Inc. (US) 2002-02-06 EP claimed
WO-2000064486-A2 ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES VECTRAMED, INC. (US) 2000-11-02 WO claimed
US-4575377-A Oxidation hair dyes comprising resorcinol derivatives as coupling components HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-03-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040228831-A1 Polymeric conjugates for tissue activated drug delivery SI, CD44, MMP1 CA2 1462/4885CAMK2A 3078/4885HSP90AB1 684/4885
US-20220142895-A1 USE OF SALIDROSIDE DERIVATIVE IN EXTERNAL PREPARATION FOR SKIN WHITENING SPG11, SORD, SP1 CA2 2040/4885CAMK2A 3375/4885HSP90AB1 2738/4885
US-12171856-B2 Use of salidroside derivative in external preparation for skin whitening SPG11, SORD, SP1 CA2 2040/4885CAMK2A 3375/4885HSP90AB1 2738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.