SCHEMBL79354

SCHEMBL79354

O=C(CBr)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 1.00
GSK3B P49841 9/20 0.67
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
ABL1 P00519 1/20 0.58
POLB P06746 1/20 0.58
ALPI P09923 1/20 0.58
GAA P10253 1/20 0.58
ALPG P10696 1/20 0.58
APEX1 P27695 1/20 0.58
CASP3 P42574 1/20 0.58
RECQL P46063 1/20 0.58
BLM P54132 1/20 0.58
CASP7 P55210 1/20 0.58
CASP6 P55212 1/20 0.58
MCL1 Q07820 1/20 0.58
RIN1 Q13671 1/20 0.58
TDP1 Q9NUW8 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5804589 0.98 PTPN1 (0.95) PTPN1GSK3BNPC1RAB9AKDM4E
4-Hydroxyacetophenone SCHEMBL4781559 0.89 PTPN1 (0.80) PTPN1GSK3BNPC1RAB9AKDM4E
SCHEMBL205280 0.89 GSK3B (0.80) PTPN1GSK3BNPC1RAB9A
SCHEMBL689331 0.82 GSK3B (0.83) PTPN1GSK3BRAB9AKDM4EALDH1A1
SCHEMBL28594745 0.82 GSK3B (0.70) PTPN1GSK3BALDH1A1ESR1ESR2
SCHEMBL27665801 0.81 PTPN1 (0.68) PTPN1NPC1RAB9AKDM4EALDH1A1
SCHEMBL247615 0.80 GSK3B (0.70) PTPN1GSK3BALDH1A1
SCHEMBL70930 0.80 GSK3B (1.00) PTPN1GSK3B
SCHEMBL9909658 0.80 GSK3B (0.67) PTPN1GSK3BKDM4EALDH1A1ABL1
SCHEMBL3987484 0.79 NPC1 (0.65) PTPN1NPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078296-A1 SUSTAINED-RELEASE SCALE INHIBITORS Materials Engineering and Technical Support Services (US) 2026-03-19 US claimed
US-20250333698-A1 SIRPa DEFICIENT MACROPHAGES FOR TREATING CANCER UNIV GEORGIA STATE RES FOUND (US) 2025-10-30 US claimed
CN-119930621-A Fungus-inhibiting matrine hydrazine thiazole derivative and preparation method and application thereof 南京林业大学 2025-05-06 CN claimed
CN-119371324-B Preparation method of deuterium-labeled ractopamine hydrochloride-d 5 成都大道三灵生物科技有限公司 2025-03-14 CN claimed
CN-119371324-A Preparation method of deuterium-labeled ractopamine hydrochloride-d 5 成都大道三灵生物科技有限公司 2025-01-28 CN claimed
US-20240374562-A1 METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS EPICENTRX, INC. (US) 2024-11-14 US claimed
CN-118702556-A Method for preparing medical intermediate from lignin and application thereof 江苏大学 2024-09-27 CN claimed
CN-117865868-B Functionalized molecule, preparation method and application thereof 湖南大学 2024-09-06 CN claimed
EP-4423251-A1 SIRP ALPHA DEFICIENT MACROPHAGES FOR TREATING CANCER Georgia State University Research Foundation, Inc. (US) 2024-09-04 EP claimed
CN-118530786-A Film stripping liquid suitable for flexible circuit board and preparation method thereof 深圳市天熙科技开发有限公司 2024-08-23 CN claimed
CN-1174830-A Method for synthesizing lecdopamine CHENGDU ORGANIC CHEM INST (CN) 1998-03-04 CN claimed
US-5654330-A CONTROLS GROWTH OF BACTERIA AND/OR FUNGI BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1997-08-05 US claimed
CN-1144455-A Synergistic antimicrobial compositons containing halogenated acetophenone and organic acid BUCKMAN LABOR INC (US) 1997-03-05 CN claimed
EP-0741517-A1 SYNERGISTIC ANTIMICROBIAL COMPOSITIONS CONTAINING A HALOGENATED ACETOPHENONE AND AN ORGANIC ACID BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1996-11-13 EP claimed
US-5527826-A Synergistic antimicrobial compositions containing a halogenated acetophenone and an organic acid BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1996-06-18 US claimed
CN-1116620-A Method for synthesis of beta-adrenomimetic excitant type fodder additive CHENGDU ORGANIC CHEM INST (CN) 1996-02-14 CN claimed
US-5441981-A Synergistic antimicrobial compositions containing a halogenated acetophenone and an organic acid BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1995-08-15 US claimed
WO-1995020319-A1 SYNERGISTIC ANTIMICROBIAL COMPOSITIONS CONTAINING A HALOGENATED ACETOPHENONE AND AN ORGANIC ACID BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1995-08-03 WO claimed
US-5107034-A Bromination of 4-hydroxyacetophenone, treating with methoxide to produce alpha-methoxy-4-hydroxyacetophenone, reduction HOECHST CELANESE CORPORATION (US) 1992-04-21 US claimed
EP-0449602-A1 Method for producing 4-(2'-methoxyethyl) phenol HOECHST CELANESE CORPORATION (US) 1991-10-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078296-A1 SUSTAINED-RELEASE SCALE INHIBITORS CEL, TST, CD44 PTPN1 2949/4885GSK3B 486/4885NPC1 2745/4885
US-20240374562-A1 METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS HBB, HBG2, HBZ PTPN1 217/4885GSK3B 3255/4885NPC1 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.