Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935696 | 0.78 | LMNA (0.33) | SIGMAR1MTNR1AMTNR1BCYP3A4MEN1 | |
| SCHEMBL7945332 | 0.73 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL7632821 | 0.71 | SIGMAR1 (0.30) | SIGMAR1MTNR1AMTNR1BCYP3A4MEN1 | |
| SCHEMBL6682538 | 0.68 | HTR2A (0.38) | SIGMAR1CYP3A4MEN1KMT2ARET | |
| SCHEMBL4360299 | 0.68 | HTR2A (0.38) | SIGMAR1CYP3A4MEN1KMT2ARET | |
| SCHEMBL8376820 | 0.65 | KDM4E (0.37) | SIGMAR1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL6763868 | 0.65 | HTR2A (0.38) | SIGMAR1CYP3A4MEN1KMT2ARET | |
| SCHEMBL2136144 | 0.65 | HTR2A (0.38) | SIGMAR1CYP3A4MEN1KMT2ARET | |
| SCHEMBL29758162 | 0.65 | HTR2A (0.38) | SIGMAR1CYP3A4MEN1KMT2ARET | |
| SCHEMBL4925283 | 0.65 | HTR2A (0.38) | SIGMAR1CYP3A4MEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046201-A1 | GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |