Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943694 | 0.79 | ELANE (0.46) | ELANEHCRTR2RAB9A | |
| SCHEMBL8208603 | 0.78 | ELANE (0.56) | ELANEHCRTR1HCRTR2 | |
| SCHEMBL4455495 | 0.74 | ACE (0.44) | ELANEHCRTR1HCRTR2 | |
| SCHEMBL4458293 | 0.74 | ACE (0.44) | ELANEHCRTR1HCRTR2 | |
| SCHEMBL4455505 | 0.74 | ACE (0.44) | ELANEHCRTR1HCRTR2 | |
| SCHEMBL4458302 | 0.74 | ACE (0.44) | ELANEHCRTR1HCRTR2 | |
| SCHEMBL7987507 | 0.74 | CNR2 (0.47) | NPC1RAB9A | |
| SCHEMBL7942699 | 0.73 | THRB (0.46) | ELANE | |
| SCHEMBL16716297 | 0.73 | CTSS (0.47) | ELANEHCRTR1HCRTR2 | |
| SCHEMBL24481955 | 0.71 | ELANE (0.42) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045266-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-04-22 | — | — | WO | disclosed |