Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997452 | 0.91 | TRPV1 (0.47) | SMN1; SMN2LMNAKCNQ1PIK3CAPIK3CD | |
| SCHEMBL7997391 | 0.89 | KCNQ1 (0.53) | SMN1; SMN2ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL7997071 | 0.88 | NPC1 (0.52) | SMN1; SMN2ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL17188760 | 0.86 | UCHL1 (0.46) | MAPTKCNQ1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL17188767 | 0.85 | RAB9A (0.51) | SMN1; SMN2ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL7999807 | 0.83 | CNR2 (0.44) | CNR2SMN1; SMN2ALDH1A1LMNAUSP2 | |
| SCHEMBL7943694 | 0.80 | ELANE (0.46) | ALDH1A1RAB9A | |
| SCHEMBL17188712 | 0.76 | — | — | |
| SCHEMBL7935872 | 0.74 | ELANE (0.45) | RAB9ANPC1 | |
| SCHEMBL8227722 | 0.73 | CTSK (0.42) | CNR2SMN1; SMN2ALDH1A1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |