Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.91 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyruvate SCHEMBL148220 | 0.95 | — | — | |
| Pyruvate SCHEMBL6743471 | 0.91 | CA4 (0.91) | CA4CA1TSHRTHPOFAHD1 | |
| Pyruvate SCHEMBL598199 | 0.91 | — | — | |
| Pyruvate SCHEMBL597752 | 0.91 | CA4 (0.91) | CA4CA1TSHRTHPOFAHD1 | |
| Pyruvate SCHEMBL597153 | 0.91 | CA4 (0.91) | CA4CA1TSHRTHPOFAHD1 | |
| Pyruvate SCHEMBL18226 | 0.91 | — | — | |
| Pyruvate SCHEMBL1332703 | 0.91 | — | — | |
| Pyruvate SCHEMBL6743473 | 0.91 | CA4 (0.91) | CA4CA1TSHRTHPOFAHD1 | |
| Pyruvate SCHEMBL3745552 | 0.91 | CA4 (0.91) | CA4CA1TSHRTHPOFAHD1 | |
| Pyruvate SCHEMBL1332958 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108384210-B | Application of pyruvate and modified polylactic acid | 中国科学院长春应用化学研究所 | 2020-07-28 | — | — | CN | claimed |
| CN-108384210-B | Application of pyruvate and modified polylactic acid | 中国科学院长春应用化学研究所 | 2020-07-28 | — | — | CN | disclosed |
| US-6232497-B1 | REACTING PYRUVIC ACID WITH ORGANOMETALLIC COMPOUNDS | SKW TROSTBERG AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-0207202-A1 | Anti-tumor platinum complexes | Kidani, Yoshinori (JP) | 1987-01-07 | — | — | EP | disclosed |
| US-4567285-A | ANTITUMOR AGENTS | YOSHINORI KIDANI (JP) | 1986-01-28 | — | — | US | disclosed |