Pyruvate

Pyruvate

SCHEMBL18226

CC(=O)C(=O)[O-].[Na+]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Pyruvate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyruvate SCHEMBL3635702 1.00 CA4 (1.00)
Pyruvate SCHEMBL1332722 1.00
Pyruvate SCHEMBL28324563 1.00 CA4 (1.00)
Pyruvate SCHEMBL1333219 1.00
Pyruvate SCHEMBL1332812 1.00
Pyruvate SCHEMBL1332703 1.00
Pyruvate SCHEMBL1332958 1.00
Pyruvate SCHEMBL1331761 1.00
Pyruvate SCHEMBL15541131 0.96
Pyruvate SCHEMBL20481652 0.96 CA4 (0.92)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 115156 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081213-A Preparation method and application of enucleated mesenchymal stem cells for in-situ release of apoptotic bodies 2026-05-26 CN claimed
CN-122081205-A Fertilization culture solution and preparation method and application thereof 2026-05-26 CN claimed
CN-122081206-A Preparation method of articular cartilage organoids, biological ink for encapsulating articular cartilage organoids, preparation method and application thereof 2026-05-26 CN claimed
CN-122080382-A Isosorbide type polycarbonate and preparation method thereof 2026-05-26 CN claimed
CN-120505386-B Method for modifying protein in open environment and protein modifier PEKING UNIVERSITY SCHOOL OF STOMATOLOGY (CN) 2026-05-26 CN claimed
CN-122081116-A Culture medium for high-density culture of mycoplasma hyorhinis and application thereof 2026-05-26 CN claimed
CN-121379932-B Culture medium for high-density serum-free suspension culture of BHK-21 cells and application thereof Zhongsheng tianxinhe (Wuxi) Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122081234-A Low-serum MSB1 suspension medium and chicken infectious anemia virus inactivated vaccine 2026-05-26 CN claimed
WO-2026104367-A1 SALMONIDAE CELL DERIVATION AND MAINTENANCE Roslin Technologies Limited (GB) 2026-05-21 WO claimed
WO-2026097260-A1 CHICKEN SERUM-FREE CULTURE MEDIUM FOR PROMOTING PROLIFERATION OF CHICKEN PRIMORDIAL GERM CELLS AND USE THEREOF 扬州大学 2026-05-15 WO claimed
EP-0110609-A1 Sterilizing treatment with hydrogen peroxide and neutralization of residual amounts thereof THE COOPER COMPANIES, INC. (formerly called CooperVision, Inc.) (US) 1984-06-13 EP claimed
US-4411993-A ANTITUMOR AND -CARCINOGENIC AGENTS IMMUNEX CORPORATION 1983-10-25 US claimed
US-4407945-A Constitutive production of interleukin 2 by a T cell hybridoma IMMUNEX CORPORATION (US) 1983-10-04 US claimed
EP-0076647-A2 Culture media for cells originating from the immune system HANA Biologics Incorporated (US) 1983-04-13 EP claimed
EP-0019054-B1 NUTRIENT MEDIUM AND ITS USE IN TESTING ANTIMICROBIAL AGENTS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-05-05 EP claimed
US-4275154-A Nutrient medium HOFFMANN-LA ROCHE INC. (US) 1981-06-23 US claimed
EP-0019054-A1 Nutrient medium and its use in testing antimicrobial agents F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-11-26 EP claimed
US-4154962-A Synthesis of hydratropic acid and some of its alkyl derivatives AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 1979-05-15 US claimed
US-4049494-A Vaccine production process THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-09-20 US claimed
US-4042733-A Forming solid, adhesive-free composite of membrane filters and cellulosic cardboard BOEHRINGER INGELHEIM GMBH (DT) 1977-08-16 US claimed