Pyruvate

Pyruvate

SCHEMBL597752

CC(=O)C(=O)[O-].CC(=O)C(=O)[O-].CC(=O)C(=O)[O-].[Al+3]

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.91
CA1 P00915 2/20 0.58
TSHR P16473 1/20 0.50
THPO P40225 1/20 0.50
FAHD1 Q6P587 1/20 0.46
LMNA P02545 2/20 0.42
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
BLM P54132 3/20 0.38
MEN1 O00255 1/20 0.38
LDHA P00338 1/20 0.38
KMT2A Q03164 1/20 0.38
PMP22 Q01453 2/20 0.36
ALOX15 P16050 1/20 0.36
THRB P10828 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyruvate SCHEMBL148220 0.95
Pyruvate SCHEMBL18226 0.91
Pyruvate SCHEMBL598199 0.91
Pyruvate SCHEMBL1331761 0.91
Pyruvate SCHEMBL1332958 0.91
Pyruvate SCHEMBL1332703 0.91
Pyruvate SCHEMBL6743471 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL7936306 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL3745552 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL597153 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118556088-A Thermally debondable adhesive 3M创新有限公司 2024-08-27 CN claimed
CN-104998264-B Methods and compositions for treating mammalian diseases and wounds caused by peroxynitrite overexpression 北方细胞制药公司 2020-09-15 CN claimed
US-20180338936-A1 Methods and Compositions for the Treatment and Prevention of Allergic Rhinitis MARTIN ALAIN (US) 2018-11-29 US claimed
US-9675569-B2 Method for treating a pulmonary disease state in mammals by up regulating indigenous in vivo levels of inflammatory agents in mammalian cells CELLULAR SCIENCES, INC. 2017-06-13 US claimed
US-20160022616-A1 Method for Treating a Pulmonary Disease State in Mammals by Up Regulating Indigenous in vivo Levels of Inflammatory Agents in Mammalian Cells CELLULAR SCIENCES, INC. 2016-01-28 US claimed
EP-1855721-B1 METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES AND INJURIES CAUSED BY THE OVER-EXPRESSION OF PEROXYNITRITE NORTH CELL PHARMACEUTICAL INC (US) 2014-09-10 EP claimed
WO-2013187891-A1 METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS MARTIN ALAIN (US) 2013-12-19 WO claimed
US-20130018334-A1 Biodegradable wound care products with biocompatible artificial skin treatment and healing accelerator NORTHCELL PHARMACEUTICAL INC. 2013-01-17 US claimed
US-8211943-B2 Method for treating a pulmonary disease state in mammals by up regulating indigenous in vivo levels of inflammatory agents in mammalian cells CELLULAR SCIENCES, INC. 2012-07-03 US claimed
US-8114907-B2 Method for treating a pulmonary disease state in mammals by up regulating indigenous in vivo levels of inflammatory agents in mammalian cells CELLULAR SCIENCES INC (US) 2012-02-14 US claimed
EP-2187738-A1 METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP OR DOWN REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS Cellular Sciences, Inc. (US) 2010-05-26 EP claimed
WO-2009020582-A1 METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP OR DOWN REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS CELLULAR SCIENCES, INC. (US) 2009-02-12 WO claimed
US-20090041738-A1 Method for treating a pulmonary disease state in mammals by up or down regulating indigenous in vivo levels of inflammatory agents in mammalian cells CELLULAR SCIENCES, INC. 2009-02-12 US claimed
US-20090041739-A1 Method for treating a pulmonary disease state in mammals by up or down regulating indigenous in vivo levels of inflammatory agents in mammalian cells CELLULAR SCIENCES, INC. 2009-02-12 US claimed
EP-1855721-A1 METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES AND INJURIES CAUSED BY THE OVER-EXPRESSION OF PEROXYNITRITE North Cell Pharmaceutical, Inc. (US) 2007-11-21 EP claimed
WO-2006086643-A1 METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES AND INJURIES CAUSED BY THE OVER-EXPRESSION OF PEROXYNITRITE NORTH CELL PHARMACEUTICAL, INC. (US) 2006-08-17 WO claimed
US-20050197397-A1 Method and composition for treating mammalian diseases and injuries caused by the over-expression of peroxynitrite NORTH CELL PHARMACEUTICAL 2005-09-08 US claimed
US-12611389-B1 Compositions and methods to reduce or eliminate nasal biofilms and mucus barriers allowing sodium pyruvate to increase the synthesis of nitric oxide and eliminate nasal infections and their toxins that cause lung, nerve and brain damage CELLULAR SCIENCES, INC. (US) 2026-04-28 US disclosed
US-20050197397-A1 Method and composition for treating mammalian diseases and injuries caused by the over-expression of peroxynitrite NORTH CELL PHARMACEUTICAL 2005-09-08 US disclosed
EP-0031805-B1 HARD BODY, ESPECIALLY HARD METAL WEARING PART, AND PROCESS FOR ITS PRODUCTION VEREINIGTE EDELSTAHLWERKE AKTIENGESELLSCHAFT (VEW) (AT) 1984-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611389-B1 Compositions and methods to reduce or eliminate nasal biofilms and mucus barriers allowing sodium pyruvate to increase the synthesis of nitric oxide and eliminate nasal infections and their toxins that cause lung, nerve and brain damage CX3CR1, CHRM3, CHRM2 CA4 1950/4885CA1 1625/4885TSHR 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.