Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Pyruvate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyruvate SCHEMBL597153 | 0.95 | CA4 (0.91) | — | |
| Pyruvate SCHEMBL7936306 | 0.95 | CA4 (0.91) | — | |
| Pyruvate SCHEMBL597752 | 0.95 | CA4 (0.91) | — | |
| Pyruvate SCHEMBL598199 | 0.95 | — | — | |
| Pyruvate SCHEMBL1331761 | 0.95 | — | — | |
| Pyruvate SCHEMBL1332703 | 0.95 | — | — | |
| Pyruvate SCHEMBL6743471 | 0.95 | CA4 (0.91) | — | |
| Pyruvate SCHEMBL18226 | 0.95 | — | — | |
| Pyruvate SCHEMBL3745552 | 0.95 | CA4 (0.91) | — | |
| Pyruvate SCHEMBL1332958 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260069911-A1 | ENVIRONMENTALLY-CLEAN FIRE INHIBITING BIOCHEMICAL COMPOSITIONS, SOLUTIONS AND POWDERS, AND METHODS OF AND APPARATUS FOR PRODUCING FIRE PROTECTED WOOD PRODUCTS | MIGHTY FIRE BREAKER LLC (US) | 2026-03-12 | — | — | US | claimed |
| US-20260069910-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE INHIBITING BIOCHEMICAL SOLUTIONS AND METHODS OF AND APPARATUS FOR APPLYING THE SAME TO PROTECT PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2026-03-12 | — | — | US | claimed |
| CN-121570446-A | Application of pyruvic acid in preparation of medicine for inhibiting neuronal cell iron death after TBI | 徐州医科大学 | 2026-02-27 | — | — | CN | claimed |
| US-20260048289-A1 | ENVIRONMENTALLY-SAFE WATER-BASED FIRE RETARDANT BIOCHEMICAL COMPOSITIONS FORMULATED USING ALKALI METAL SALTS, FREE FROM PHOSPHATES, NITRATES, AND AMMONIUM-SALTS, FOR NON-CORROSIVE AERIAL AND GROUND DELIVERY ONTO PROPERTY REQUIRING LONG-TERM PROTECTION AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2026-02-19 | — | — | US | claimed |
| US-20260014403-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE INHIBITING BIOCHEMICAL COMPOSITIONS, SOLUTIONS, POWDERS AND METHODS OF AND APPARATUS FOR PRODUCING FIRE PROTECTED WOOD AND ENGINEERED WOOD PRODUCTS | MIGHTY FIRE BREAKER LLC (US) | 2026-01-15 | — | — | US | claimed |
| WO-2025245031-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE-INHIBITING BIOCHEMICAL SOLUTIONS, METHODS, AND APPARATUS FOR APPLYING TO PROTECT PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2025-11-27 | — | — | WO | claimed |
| US-20250128105-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE INHIBITING BIOCHEMICAL SOLUTIONS FORMULATED USING ALKALI METAL SALTS OF PYRUVIC ACID FOR PROTECTING PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2025-04-24 | — | — | US | claimed |
| WO-2025034579-A1 | METHODS FOR PREPARATION OF BIOCOMPATIBLE SOLUTIONS WITH SABRE HYPERPOLARIZATION | VIZMA LIFE SCIENCES, INC. (US) | 2025-02-13 | — | — | WO | claimed |
| CN-119263979-A | Mitochondrion targeting copper ion carrier anticancer drug and preparation method and application thereof | 北京科技大学 | 2025-01-07 | — | — | CN | claimed |
| US-20240366982-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE INHIBITING BIOCHEMICAL COMPOSITIONS AND METHODS OF AND APPARATUS FOR APPLYING THE SAME TO PROTECT PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2024-11-07 | — | — | US | claimed |
| US-5395822-A | Use of pyruvate to prevent neuronal degeneration associated with ischemia | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1995-03-07 | — | — | US | claimed |
| EP-0627917-A1 | CYTOPROTECTIVE COMPOSITIONS CONTAINING PYRUVATE AND ANTIOXIDANTS | WARNER-LAMBERT COMPANY (US) | 1994-12-14 | — | — | EP | claimed |
| EP-0614359-A1 | WOUND HEALING COMPOSITIONS CONTAINING A PYRUVATE, AN ANTIOXIDANT AND A MIXTURE OF FATTY ACIDS | WARNER-LAMBERT COMPANY (US) | 1994-09-14 | — | — | EP | claimed |
| EP-0573465-A1 | THERAPEUTIC COMPOSITIONS TO PROTECT AND RESUSCITATE MAMMALIAN CELLS AND METHODS FOR PREPARING AND USING SAME. | WARNER LAMBERT CO (US) | 1993-12-15 | — | — | EP | claimed |
| WO-1993016690-A1 | CYTOPROTECTIVE COMPOSITIONS CONTAINING PYRUVATE AND ANTIOXIDANTS | WARNER-LAMBERT COMPANY (US) | 1993-09-02 | — | — | WO | claimed |
| WO-1993010776-A1 | WOUND HEALING COMPOSITIONS CONTAINING A PYRUVATE, AN ANTIOXIDANT AND A MIXTURE OF FATTY ACIDS | WARNER-LAMBERT COMPANY (US) | 1993-06-10 | — | — | WO | claimed |
| WO-1992015292-A1 | THERAPEUTIC COMPOSITIONS TO PROTECT AND RESUSCITATE MAMMALIAN CELLS AND METHODS FOR PREPARING AND USING SAME | WARNER-LAMBERT COMPANY (US) | 1992-09-17 | — | — | WO | claimed |
| EP-0387058-A1 | Process for preparing benzylpyruvic acids and esters | MERCK & CO. INC. (US) | 1990-09-12 | — | — | EP | claimed |
| US-4956490-A | Process for preparing benzylpyruvic acids and esters | MERCK & CO., INC. (US) | 1990-09-11 | — | — | US | claimed |
| US-4939085-A | Oxidized coenzyme-containing dry analytical element | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-03 | — | — | US | claimed |