Pyruvate

Pyruvate

SCHEMBL6743471

CC(=O)C(=O)[O-].CC(=O)C(=O)[O-].CC(=O)C(=O)[O-].CC(=O)C(=O)[O-].[Pb+4]

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.91
CA1 P00915 2/20 0.58
TSHR P16473 1/20 0.50
THPO P40225 1/20 0.50
FAHD1 Q6P587 1/20 0.46
LMNA P02545 2/20 0.42
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
BLM P54132 3/20 0.38
MEN1 O00255 1/20 0.38
LDHA P00338 1/20 0.38
KMT2A Q03164 1/20 0.38
PMP22 Q01453 2/20 0.36
ALOX15 P16050 1/20 0.36
THRB P10828 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyruvate SCHEMBL148220 0.95
Pyruvate SCHEMBL18226 0.91
Pyruvate SCHEMBL6743473 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL598199 0.91
Pyruvate SCHEMBL1332958 0.91
Pyruvate SCHEMBL7936306 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL1332703 0.91
Pyruvate SCHEMBL597153 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL3745552 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL597752 0.91 CA4 (0.91) CA4CA1TSHRTHPOFAHD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220170056-A1 COMPOSITIONS AND METHODS FOR BIOSYNTHESIS OF TERPENOIDS OR CANNABINOIDS IN A HETEROLOGOUS SYSTEM INMED PHARMACEUTICALS INC. (CA) 2022-06-02 US disclosed
EP-3935178-A1 COMPOSITIONS AND METHODS FOR BIOSYNTHESIS OF TERPENOIDS OR CANNABINOIDS IN A HETEROLOGOUS SYSTEM Inmed Pharmaceuticals Inc. (CA) 2022-01-12 EP disclosed
EP-2861715-B1 CATALASE IN GROWTH MEDIA EUCODIS BIOSCIENCE GMBH (AT) 2018-09-19 EP disclosed
US-9951306-B2 Catalase in growth media EUCODIS BIOSCIENCE GMBH (AT) 2018-04-24 US disclosed
US-20150152466-A1 CATALASE IN GROWTH MEDIA BIOSYNTH GMBH (AT) 2015-06-04 US disclosed
EP-2861715-A1 CATALASE IN GROWTH MEDIA Eucodis Bioscience GmbH (AT) 2015-04-22 EP disclosed
WO-2013186253-A1 CATALASE IN GROWTH MEDIA EUCODIS BIOSCIENCE GMBH (AT) 2013-12-19 WO disclosed
US-20040132813-A1 Glycerol-lactate esters for use as an energy supplement during exercise and recovery BROOKS GEORGE A (US) 2004-07-08 US disclosed
US-6743821-B2 CONTROLLING BLOOD GLUCOSE CONCENTRATION BROOKS GEORGE A (US) 2004-06-01 US disclosed
US-20030013763-A1 Glycerol-lactate esters for use as an energy supplement during exercise and recovery BROOKS GEORGE A (US) 2003-01-16 US disclosed
US-6482853-B1 Lactate thiolester for cardiac energy resuscitation and prevention of reperfusion injury and use as an energy supplement during exercise and recovery BROOKS GEORGE A (US) 2002-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030013763-A1 Glycerol-lactate esters for use as an energy supplement during exercise and recovery GYS1, PYGM, GYS2 CA4 1398/4885CA1 2201/4885TSHR 2671/4885
US-20040132813-A1 Glycerol-lactate esters for use as an energy supplement during exercise and recovery GYS1, PYGM, GYS2 CA4 1398/4885CA1 2201/4885TSHR 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.