SCHEMBL7937462

SCHEMBL7937462

O=C(OP(=O)(O)O)[C@@H]1CCCN1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.40
DPP8 Q6V1X1 3/20 0.40
DPP9 Q86TI2 2/20 0.40
NOS2 P35228 2/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
FDPS P14324 1/20 0.36
FAP Q12884 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
PRCP P42785 1/20 0.35
ANPEP P15144 1/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29761126 0.85 NOS2 (0.41) DPP4DPP8DPP9NOS2NOS3
SCHEMBL995604 0.77 NOS2 (0.46) DPP4DPP8DPP9NOS2NOS3
SCHEMBL146828 0.77 NOS2 (0.46) DPP4DPP8DPP9NOS2NOS3
SCHEMBL6859669 0.77 NOS2 (0.46) DPP4DPP8DPP9NOS2NOS3
SCHEMBL388496 0.75
SCHEMBL1268174 0.75
SCHEMBL464808 0.75
SCHEMBL29131673 0.74 NOS2 (0.41) DPP4DPP8DPP9NOS2NOS3
SCHEMBL11303643 0.74 FDPS (0.38) DPP4NOS2NOS3NOS1FDPS
SCHEMBL23679866 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118021694-A An antiaging composition containing aloe extract 方红梅 2024-05-14 CN claimed
CN-118021694-A An antiaging composition containing aloe extract 方红梅 2024-05-14 CN disclosed
CN-114345919-B Method for leaching and repairing arsenic-polluted soil by amino acid ionic liquid 江南大学 2022-10-11 CN disclosed
CN-114345919-A Method for restoring arsenic-polluted soil by leaching amino acid ionic liquid 江南大学 2022-04-15 CN disclosed
CN-107880708-B Waterproof durable fireproof wood and preparation method thereof 卢子强 2020-09-22 CN disclosed
EP-3541413-A2 AQUEOUS PHARMACEUTICAL FORMULATIONS Polpharma Biologics S.A. (PL) 2019-09-25 EP disclosed
CN-105102428-B Novel DPP-IV inhibitors DNJ制药有限公司 2018-11-16 CN disclosed
WO-2018091729-A2 AQUEOUS PHARMACEUTICAL FORMULATIONS ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) 2018-05-24 WO disclosed
CN-107880708-A A kind of water-fast durable fireproof wood and preparation method thereof 卢子强 2018-04-06 CN disclosed
CN-101035568-A Combination therapy using transferrin fusion proteins comprising GLP-1 BIOREXIS PHARMACEUTICAL CORP (US) 2007-09-12 CN disclosed
US-6258597-B1 CONTACTING UMBILICAL CORD BLOOD OR BONE MARROW CELLS WITH INHIBITOR OF DIPEPTIDYLPEPTIDASE TYPE IV TO INCREASE NUMBER OR DIFFERENTIATION STATE; DOES NOT USE EXOGENOUS CYTOKINE POINT THERAPEUTICS, INC. 2001-07-10 US disclosed