Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 5/20 | 0.46 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29515444 | 0.82 | TRIM58 (0.37) | YTHDC1EGFRTRIM58PDE4APDE4B | |
| SCHEMBL16094412 | 0.81 | SLC29A1 (0.42) | YTHDC1YTHDF2KHKCA1CA2 | |
| SCHEMBL7937489 | 0.80 | MAP4K4 (0.37) | YTHDC1YTHDF2EGFRKHKMAP4K4 | |
| SCHEMBL7939938 | 0.78 | YTHDC1 (0.49) | YTHDC1YTHDF2ADORA3 | |
| SCHEMBL16094713 | 0.78 | SLC29A1 (0.42) | EGFRKHKALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL16094548 | 0.77 | SLC29A1 (0.41) | EGFRKHKALDH1A1LMNAHTT | |
| SCHEMBL7937484 | 0.68 | SLC29A1 (0.39) | KHKMAP4K4CA1CA2CA9 | |
| SCHEMBL11876693 | 0.67 | XDH (0.39) | YTHDC1YTHDF2PDPK1TRIM58PDE4A | |
| SCHEMBL7937472 | 0.66 | SLC29A1 (0.51) | KHKCA1CA2CA9ALDH1A1 | |
| SCHEMBL25762070 | 0.66 | PDPK1 (0.39) | YTHDC1YTHDF2EGFRPDPK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |