Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939003 | 0.88 | DRD2 (0.34) | DRD2DRD3 | |
| SCHEMBL28679348 | 0.85 | DRD2 (0.43) | DRD2DRD3HTR1A | |
| SCHEMBL7942550 | 0.81 | SLC6A3 (0.38) | — | |
| SCHEMBL7938959 | 0.77 | DRD2 (0.34) | DRD2DRD3 | |
| SCHEMBL2237897 | 0.76 | SLC6A3 (0.39) | — | |
| SCHEMBL2421840 | 0.76 | SLC6A3 (0.39) | — | |
| SCHEMBL4351374 | 0.76 | DRD2 (0.38) | DRD2DRD3HTR1A | |
| SCHEMBL27909472 | 0.74 | DRD2 (0.50) | DRD2DRD3HTR1A | |
| SCHEMBL9681051 | 0.72 | HTR1A (0.36) | DRD2DRD3HTR1A | |
| SCHEMBL7930899 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |