Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15358854 | 0.78 | LTA4H (0.45) | TSHRLTA4HCA4ALDH1A1MEN1 | |
| SCHEMBL153060 | 0.78 | ALDH1A1 (0.50) | TSHRLTA4HCA4ALDH1A1MEN1 | |
| SCHEMBL632465 | 0.78 | LTA4H (0.45) | TSHRLTA4HCA4ALDH1A1MEN1 | |
| SCHEMBL9319424 | 0.78 | LTA4H (0.45) | TSHRLTA4HCA4ALDH1A1MEN1 | |
| SCHEMBL7766235 | 0.75 | LDHA (0.47) | ALDH1A1MEN1MAPTKMT2AALOX15 | |
| SCHEMBL3430657 | 0.75 | — | — | |
| SCHEMBL9529296 | 0.75 | — | — | |
| SCHEMBL25006052 | 0.74 | CA4 (0.43) | TSHRLTA4HCA4ALDH1A1MEN1 | |
| SCHEMBL9676942 | 0.74 | LTA4H (0.41) | TSHRLTA4HCA4ALDH1A1MEN1 | |
| SCHEMBL5245164 | 0.74 | LMNA (0.41) | TSHRLTA4HCA4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016151295-A1 | FLUORINATION PROCESS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2016-09-29 | — | — | WO | disclosed |
| EP-1138657-A1 | Process for generating electrophiles from anions by reaction with electrophilic fluorinating agent | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6270843-B1 | REACTING A SALT COMPRISING ANIONIC FORM OF SUBSTITUENT WITH AN ELECTROPHILIC FLUORINATION AGENT TO PROVIDE AN ELECTROPHILE COMPRISING CATIONIC FORM OF SUBSTITUENT; ELECTROPHILICALLY SUBSTITUTING ELECTROPHILE ON SUBSTRATE | AIR PRODUCTS AND CHEMICALS, INC. | 2001-08-07 | — | — | US | disclosed |