Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7926982 | 0.82 | ADRA2A (0.32) | ADRA2AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL3691671 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7217384 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL30525914 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7935307 | 0.79 | ADRA2A (0.30) | ADRA2AADRA1DADRA1A | |
| Hexane SCHEMBL8607037 | 0.78 | SOAT1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7724553 | 0.76 | CHRNB2 (0.31) | ADRA2AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL4249925 | 0.76 | PDCD1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5604826 | 0.76 | BRD4 (0.33) | ADRA2AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL27463818 | 0.76 | PDCD1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |