SCHEMBL7938765

SCHEMBL7938765

N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1B(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 1.00
DPP7 Q9UHL4 13/20 1.00
DPP8 Q6V1X1 12/20 1.00
DPP9 Q86TI2 12/20 1.00
FAP Q12884 11/20 1.00
PREP P48147 3/20 0.60
PITRM1 Q5JRX3 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3092652 1.00 DPP4 (1.00) DPP4DPP7DPP8DPP9FAP
SCHEMBL3092661 1.00 DPP4 (1.00) DPP4DPP7DPP8DPP9FAP
SCHEMBL12340775 0.92 DPP4 (0.85) DPP4DPP7DPP8DPP9FAP
SCHEMBL7932223 0.87 DPP4 (0.78) DPP4DPP7DPP8DPP9FAP
SCHEMBL8228598 0.86 DPP4 (1.00) DPP4DPP7DPP8DPP9FAP
SCHEMBL12340772 0.86 DPP4 (1.00) DPP4DPP7DPP8DPP9FAP
SCHEMBL7943687 0.86 DPP4 (0.78) DPP4DPP7DPP8DPP9FAP
SCHEMBL12340760 0.85 DPP4 (1.00) DPP4DPP7DPP8DPP9FAP
SCHEMBL15334549 0.84 DPP4 (1.00) DPP4DPP7DPP8DPP9FAP
SCHEMBL12657353 0.84 DPP4 (1.00) DPP4DPP7DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-07-25 US claimed
EP-3558298-B1 ANTIDIABETIC SPIROCHROMAN COMPOUNDS MERCK SHARP & DOHME LLC (US) 2026-03-11 EP disclosed
EP-4706663-A2 FAP-ACTIVATED PROTEASOME INHIBITORS FOR TREATING SOLID TUMORS Trustees Of Tufts College (US) 2026-03-11 EP disclosed
US-20250367304-A1 FAP-ACTIVATED PROTEASOME INHIBITORS FOR TREATING SOLID TUMORS TUFTS COLLEGE (US) 2025-12-04 US disclosed
EP-4144354-B1 FAP-ACTIVATED PROTEASOME INHIBITORS FOR TREATING SOLID TUMORS TUFTS COLLEGE (US) 2025-11-26 EP disclosed
US-20250346646-A1 COMPOUNDS USEFUL TO TREAT METABOLIC DISORDERS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-11-13 US disclosed
US-20250312353-A1 DRUG REPURPOSING FOR TREATMENT OF CONGENITAL VASCULAR MALFORMATIONS UNIVERSITY OF SOUTH CAROLINA (US) 2025-10-09 US disclosed
EP-4619417-A1 NANOCONJUGATES CONTAINING PDGFR-BETA LIGANDS AND USES THEREOF Universitat Autònoma de Barcelona (ES) 2025-09-24 EP disclosed
EP-2958562-B1 ANTIDIABETIC BICYCLIC COMPOUNDS MERCK SHARP & DOHME LLC (US) 2025-09-10 EP disclosed
US-12390422-B2 Transdermal drug delivery patch, drug delivery system and drug delivery Passport Technologies, Inc. (US) 2025-08-19 US disclosed
US-8268880-B2 Soft protease inhibitors and pro-soft forms thereof TRUSTEES OF TUFTS COLLEGE (US) 2012-09-18 US disclosed
WO-2011143522-A2 ENHANCED HOMING AND ENGRAFTMENT OF HEMATOPOIETIC STEM CELLS USING BOROPROLINE COMPOUNDS DARA BIOSCIENCES, INC. (US) 2011-11-17 WO disclosed
US-20090124559-A1 Soft Protease Inhibitors and Pro-Soft Forms Thereof TRUSTEES OF TUFTS COLLEGE OFFICE OF TECHNOLOGY AND INDUSTRY COLLABORATION (US) 2009-05-14 US disclosed
US-20090124559-A1 Soft Protease Inhibitors and Pro-Soft Forms Thereof TRUSTEES OF TUFTS COLLEGE OFFICE OF TECHNOLOGY AND INDUSTRY COLLABORATION (US) 2009-05-14 US disclosed
US-20090062235-A1 Inhibitors of Dipeptidylpeptidase IV TRUSTEES OF TUFTS COLLEGE (US) 2009-03-05 US disclosed
US-20070072830-A1 Methods for treating diabetes POINT THERAPEUTICS, INC. (US) 2007-03-29 US disclosed
US-20070072830-A1 Methods for treating diabetes POINT THERAPEUTICS, INC. (US) 2007-03-29 US disclosed
WO-2006034435-A2 METHODS AND COMPOSITIONS FOR TREATING GLUCOSE-ASSOCIATED CONDITIONS, METABOLIC SYNDROME, DYSLIPIDEMIAS AND OTHER CONDITIONS POINT THERAPEUTICS, INC. (US) 2006-03-30 WO disclosed
US-20060063719-A1 Methods for treating diabetes POINT THERAPEUTICS, INC. (US) 2006-03-23 US disclosed
US-20060063719-A1 Methods for treating diabetes POINT THERAPEUTICS, INC. (US) 2006-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062235-A1 Inhibitors of Dipeptidylpeptidase IV DPP4, DPP3, DPP7 DPP4 1/4885DPP7 3/4885DPP8 9/4885
US-20060063719-A1 Methods for treating diabetes IAPP, SLC5A2, SLC2A3 DPP4 5/4885DPP7 21/4885DPP8 51/4885
US-20250367304-A1 FAP-ACTIVATED PROTEASOME INHIBITORS FOR TREATING SOLID TUMORS FAP, PSMA1, PSMB1 DPP4 442/4885DPP7 363/4885DPP8 313/4885
US-20090124559-A1 Soft Protease Inhibitors and Pro-Soft Forms Thereof PREP, DPP4, PEPD DPP4 2/4885DPP7 8/4885DPP8 13/4885
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, EFNA1, EML4 DPP4 4643/4885DPP7 4750/4885DPP8 4705/4885
US-20070072830-A1 Methods for treating diabetes IAPP, SLC5A2, SLC2A3 DPP4 5/4885DPP7 21/4885DPP8 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.