Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950460 | 0.84 | HDAC1 (0.46) | NPC1RAB9AMAPK1 | |
| SCHEMBL7666786 | 0.83 | RAB9A (0.46) | KMT2AHTTNPC1RAB9AMEN1 | |
| SCHEMBL6819653 | 0.83 | KDM4E (0.48) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL7945599 | 0.80 | RAB9A (0.61) | L3MBTL1KMT2AHTTNPC1RAB9A | |
| SCHEMBL7939137 | 0.80 | GAA (0.45) | L3MBTL1KMT2AHTTNPC1RAB9A | |
| SCHEMBL6815733 | 0.80 | PLAU (0.48) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL6815400 | 0.78 | LMNA (0.49) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL6819683 | 0.77 | SMN1; SMN2 (0.47) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL7945400 | 0.77 | SMN1; SMN2 (0.41) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL25223941 | 0.77 | NPC1 (0.56) | L3MBTL1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |