Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816160 | 0.82 | HTT (0.55) | RAB9ASMN1; SMN2L3MBTL1HDAC1HDAC6 | |
| SCHEMBL7950460 | 0.81 | HDAC1 (0.46) | RAB9AHDAC1HDAC6NPC1 | |
| SCHEMBL6815576 | 0.81 | KDM4E (0.52) | SMN1; SMN2ALDH1A1MAPTGAALMNA | |
| SCHEMBL6814321 | 0.81 | KDM4E (0.41) | RAB9ASMN1; SMN2L3MBTL1HDAC1HDAC6 | |
| SCHEMBL6819653 | 0.80 | KDM4E (0.48) | RAB9ASMN1; SMN2L3MBTL1POLBALDH1A1 | |
| SCHEMBL7938992 | 0.80 | L3MBTL1 (0.44) | RAB9AL3MBTL1POLBALDH1A1MAPT | |
| SCHEMBL7666786 | 0.80 | RAB9A (0.46) | RAB9ASMN1; SMN2POLBALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3716561 | 0.79 | CTSD (0.48) | RAB9ASMN1; SMN2L3MBTL1POLBALDH1A1 | |
| SCHEMBL7692028 | 0.79 | HDAC1 (0.52) | RAB9ASMN1; SMN2HDAC1HDAC6POLB | |
| SCHEMBL6814925 | 0.79 | SMN1; SMN2 (0.44) | RAB9ASMN1; SMN2L3MBTL1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |