Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930912 | 0.83 | MEN1 (0.59) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7930879 | 0.82 | NPY5R (0.58) | MAPTMEN1GAAKMT2ANPC1 | |
| SCHEMBL27248379 | 0.81 | PRKD3 (0.55) | MEN1KMT2ARAB9ASMN1; SMN2TTBK1 | |
| SCHEMBL4846337 | 0.79 | TTBK1 (0.43) | MEN1KMT2ATTBK1TTBK2MKNK1 | |
| SCHEMBL31086656 | 0.77 | KMT2A (0.47) | MAPTMEN1GAAKMT2ANPC1 | |
| SCHEMBL183098 | 0.76 | YTHDC1 (0.64) | NPC1CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL13351818 | 0.74 | KMT2A (0.51) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8901627 | 0.74 | NPY5R (0.72) | MAPTMEN1GAAKMT2ANPC1 | |
| SCHEMBL3500246 | 0.74 | NFKB1 (0.69) | MAPTMEN1GAAKMT2ANPC1 | |
| SCHEMBL9390360 | 0.74 | MAPT (0.69) | MAPTMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |