Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595045 | 0.89 | GPR35 (0.56) | GPR35ALDH1A1ALOX15ALOX12TYR | |
| SCHEMBL4319781 | 0.78 | GPR35 (0.55) | GPR35ALDH1A1ALOX15ALOX12KDM4E | |
| SCHEMBL4457398 | 0.78 | GPR35 (0.55) | GPR35ALDH1A1ALOX15ALOX12KDM4E | |
| SCHEMBL29426960 | 0.77 | ADRB1 (0.61) | ALDH1A1ALOX15ALOX12TYRHTT | |
| SCHEMBL51528 | 0.77 | ADRB1 (0.61) | ALDH1A1ALOX15ALOX12TYRHTT | |
| SCHEMBL1026668 | 0.76 | ALDH1A1 (0.56) | GPR35ALDH1A1ALOX15ALOX12TYR | |
| Formaldehyde SCHEMBL27575605 | 0.75 | KDM4E (0.57) | ALDH1A1ALOX15ALOX12TYRHTT | |
| SCHEMBL6351865 | 0.75 | ADRB1 (0.59) | ALDH1A1ALOX15ALOX12TYRHTT | |
| Ethane SCHEMBL16736754 | 0.75 | ADRB1 (0.59) | ALDH1A1ALOX15ALOX12TYRHTT | |
| Hydrogen Peroxide SCHEMBL11040445 | 0.75 | ADRB1 (0.59) | ALDH1A1ALOX15ALOX12TYRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262113-B1 | HYDROXY- OR MERCAPTO-PHENYLUREAS | SMITHKLINE BEECHAM CORPORATION | 2001-07-17 | — | — | US | disclosed |