Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 8/20 | 0.64 |
| ▸ | CTSK | P43235 | 6/20 | 0.64 |
| ▸ | CTSL | P07711 | 7/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944510 | 0.93 | CTSB (0.56) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL7941933 | 0.91 | CTSK (0.57) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL10537671 | 0.87 | CTSL (0.54) | CTSBCTSKCTSLCTSS | |
| SCHEMBL6485735 | 0.83 | CTSB (0.51) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL14405782 | 0.82 | ALDH1A1 (0.57) | CTSBCTSKCTSLCTSS | |
| SCHEMBL10535416 | 0.82 | KYNU (0.59) | CTSBCTSKCTSLCTSS | |
| SCHEMBL2519860 | 0.82 | KYNU (0.59) | CTSBCTSKCTSLCTSS | |
| SCHEMBL924114 | 0.81 | PPARA (0.53) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL1162401 | 0.81 | PPARA (0.53) | CTSBCTSKCTSLCTSSCASP1 | |
| SCHEMBL924112 | 0.81 | PPARA (0.53) | CTSBCTSKCTSLCTSSCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245938-B1 | COMPOUND SUITABLE FOR USE BOTH AS DERIVATIZING GROUP FOR OPTICAL SEPARATION OF ENANTIOMERS AND AS PROTECTING GROUP FOR PREPARATION OF MISACYLATED TRNA | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2001-06-12 | — | — | US | disclosed |