Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.71 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.71 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269575 | 0.86 | CASP3 (0.55) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL22493564 | 0.85 | NPC1 (0.61) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL4793005 | 0.85 | RIPK1 (0.61) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL11348242 | 0.85 | NPC1 (0.63) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL2933095 | 0.85 | CASP3 (0.53) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL22887391 | 0.84 | CASP3 (0.68) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL5053299 | 0.84 | NPC1 (0.87) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL29784265 | 0.83 | CASP3 (0.77) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL29941485 | 0.83 | CASP3 (1.00) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL3704691 | 0.83 | CASP3 (1.00) | CASP3SENP8SENP7SENP6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |
| US-4057530-A | STABILIZERS FOR VINYL CHLORIDE POLYMERS | LABAZ (FR) | 1977-11-08 | — | — | US | disclosed |