Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942667 | 0.89 | STAT6 (0.44) | STAT6AKR1C3CYP51A1DRD2CCKBR | |
| SCHEMBL7945427 | 0.87 | STAT6 (0.45) | STAT6AKR1C3CYP51A1HCRTR1DRD2 | |
| SCHEMBL14980442 | 0.87 | STAT6 (0.48) | STAT6AKR1C3CYP51A1DRD2CCKBR | |
| SCHEMBL7934440 | 0.87 | STAT6 (0.48) | STAT6AKR1C3CYP51A1DRD2CCKBR | |
| SCHEMBL19856980 | 0.86 | DRD2 (0.39) | STAT6PDE4BAKR1C3CYP51A1DRD4 | |
| SCHEMBL19856978 | 0.86 | DRD2 (0.39) | STAT6PDE4BAKR1C3CYP51A1DRD4 | |
| SCHEMBL7941165 | 0.86 | STAT6 (0.46) | STAT6PDE4BAKR1C3CYP51A1DRD3 | |
| SCHEMBL7943634 | 0.85 | STAT6 (0.48) | STAT6AKR1C3CYP51A1DRD3HTR1A | |
| SCHEMBL7945428 | 0.85 | STAT6 (0.44) | STAT6CYP51A1DRD3DRD2CCKBR | |
| SCHEMBL7941646 | 0.85 | STAT6 (0.45) | STAT6AKR1C3CYP51A1DRD2CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011912-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |