Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674678 | 1.00 | HAO1 (0.53) | HAO1S1PR1S1PR5RORCMITF | |
| SCHEMBL3289619 | 0.95 | HTT (0.55) | HAO1S1PR1S1PR5RORCMITF | |
| SCHEMBL26089356 | 0.94 | CA2 (0.50) | HAO1S1PR1S1PR5RORCMITF | |
| SCHEMBL925698 | 0.90 | CA2 (0.54) | S1PR1S1PR5CA2CAMK2AHTT | |
| SCHEMBL11478386 | 0.84 | S1PR1 (0.51) | HAO1S1PR1S1PR5MITFKLF5 | |
| SCHEMBL9751108 | 0.84 | RORC (0.52) | HAO1RORCMITFKLF5HTR2C | |
| SCHEMBL7941807 | 0.84 | CA2 (0.50) | HAO1RORCCA2HTR2CHTR2B | |
| SCHEMBL1089454 | 0.83 | HAO1 (0.51) | HAO1S1PR1S1PR5RORCMITF | |
| SCHEMBL1088973 | 0.83 | HAO1 (0.51) | HAO1S1PR1S1PR5RORCMITF | |
| SCHEMBL4651687 | 0.82 | FFAR4 (0.57) | HAO1S1PR1S1PR5MITFKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | US | claimed |
| US-20080096874-A1 | Oxadiazole Derivative as Dgat Inhibitors | ASTRAZENECA AB (SE) | 2008-04-24 | — | — | US | claimed |
| EP-1833806-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | claimed |
| WO-2006064189-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | claimed |
| CN-114656363-A | Synthetic method of palladium-catalyzed aromatic ester compound | 南京林业大学 | 2022-06-24 | — | — | CN | disclosed |
| US-20170174840-A1 | MOISTURE CURABLE SILICONE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. | 2017-06-22 | — | — | US | disclosed |
| EP-3102325-A1 | MOISTURE CURABLE SILICONE COMPOSITION | Momentive Performance Materials Inc. (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015119904-A1 | MOISTURE CURABLE SILICONE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-08-13 | — | — | WO | disclosed |
| WO-2014210492-A1 | MOISTURE CURABLE COMPOSITION WITH STRONTIUM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | US | disclosed |
| US-7795283-B2 | Oxadiazole derivative as DGAT inhibitors | ASTRAZENECA AB (SE) | 2010-09-14 | — | — | US | disclosed |
| US-20080096874-A1 | Oxadiazole Derivative as Dgat Inhibitors | ASTRAZENECA AB (SE) | 2008-04-24 | — | — | US | disclosed |
| EP-0143978-B1 | PROCESS FOR MAKING LOW CRYSTALLINITY POLYOLEFINS | HERCULES INCORPORATED (US) | 1988-03-16 | — | — | EP | disclosed |
| EP-0108489-B1 | METHOD FOR PREPARING AN IMPROVED CATALYST SUPPORT | Himont Incorporated (US) | 1986-12-10 | — | — | EP | disclosed |
| US-4540756-A | COORDINATION CATALYST OF MAGNESIUM CARBOXYLATE, ORGANOALUMINUM HALIDE, AND GROUP 4B HALIDE | HERCULES INCORPORATED (US) | 1985-09-10 | — | — | US | disclosed |
| US-4532313-A | Contacting hydrocarbon solutions of magnesium alkanoate and alkylaluminum dichloride in liquid hydrocarbon medium containing alkylaluminum alkanoate chloride | HIMONT INCORPORATED (US) | 1985-07-30 | — | — | US | disclosed |
| EP-0032294-B1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION | Himont Incorporated (US) | 1985-05-15 | — | — | EP | disclosed |
| EP-0108489-A1 | Method for preparing an improved catalyst support | Himont Incorporated (US) | 1984-05-16 | — | — | EP | disclosed |
| EP-0032294-A2 | Solid catalyst component for olefin polymerization | Himont Incorporated (US) | 1981-07-22 | — | — | EP | disclosed |
| US-4277372-A | TITANIUM CHLORIDE DEPOSITED ON MAGNESIUM CHLORIDE SUPPORT | HERCULES INCORPORATED (US) | 1981-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | DGAT1, DGAT2, GPR119 | HAO1 1499/4885S1PR1 2815/4885S1PR5 3041/4885 |
| US-20080096874-A1 | Oxadiazole Derivative as Dgat Inhibitors | DGAT1, DGAT2, GPR119 | HAO1 1599/4885S1PR1 2931/4885S1PR5 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.