Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943120 | 0.88 | ALOX5 (0.46) | ALOX5APPCYP4F2CYP4A11TDP1 | |
| SCHEMBL7942317 | 0.87 | LTA4H (0.43) | ALOX5CYP4F2CYP4A11CYP3A4 | |
| SCHEMBL7933761 | 0.86 | APP (0.52) | ALOX5APPCYP4F2CYP4A11TDP1 | |
| SCHEMBL7944778 | 0.83 | ALOX5 (0.39) | ALOX5APPSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7792671 | 0.83 | FFAR1 (0.47) | ALOX5NR3C1OR51E2 | |
| SCHEMBL6567361 | 0.82 | NR3C1 (0.44) | NR3C1NR3C2CYP3A4 | |
| SCHEMBL7944894 | 0.81 | ALOX5 (0.38) | ALOX5APPCYP4F2CYP4A11TDP1 | |
| SCHEMBL6567742 | 0.81 | TNKS2 (0.45) | ALOX5NR3C1NR3C2 | |
| SCHEMBL7933767 | 0.81 | ALDH1A1 (0.41) | ALOX5APPCYP4F2CYP4A11TDP1 | |
| SCHEMBL7942500 | 0.80 | KMT2A (0.37) | ALOX5APPCYP4F2CYP4A11TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |