SCHEMBL7944778

SCHEMBL7944778

COc1ccc(CCCC(=O)OCCO)cc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
PLAAT3 P53816 1/20 0.39
PLAAT5 Q96KN8 1/20 0.39
PLAAT2 Q9NWW9 1/20 0.39
PLAAT4 Q9UL19 1/20 0.39
HPGD P15428 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KCNH2 Q12809 1/20 0.38
TMEM97 Q5BJF2 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7943120 0.93 ALOX5 (0.46) ALOX5KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL7933553 0.85 APP (0.48) ALDH1A1LMNAL3MBTL1APP
SCHEMBL8430386 0.85 ALOX5 (0.43) ALOX5ALDH1A1MAPTLMNAPPARG
SCHEMBL7944826 0.84 VCAM1 (0.40) ALOX5KCNH2
SCHEMBL7942316 0.83 ALOX5 (0.43) ALOX5ALDH1A1MAPTSMN1; SMN2KCNH2
SCHEMBL6567720 0.81 TNKS2 (0.49) ALOX5HPGDKMT2AALDH1A1LMNA
SCHEMBL7933616 0.81 GAA (0.49) HPGDKMT2AALDH1A1MAPTLMNA
SCHEMBL7941161 0.81 CYP4F2 (0.48) ALOX5HPGDKMT2AALDH1A1APP
SCHEMBL6565864 0.80 TUBB4A (0.47) HPGDKMT2AALDH1A1LMNAPPARG
SCHEMBL7942317 0.80 LTA4H (0.43) ALOX5PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed