Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | RARA | P10276 | 2/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.49 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788052 | 0.83 | ACMSD (0.61) | RARARARBRARGCTRCACMSD | |
| SCHEMBL2036894 | 0.83 | ACMSD (0.61) | RARARARBRARGCTRCACMSD | |
| SCHEMBL7625624 | 0.82 | RARA (0.54) | CASP3SENP8SENP7SENP6RARA | |
| SCHEMBL17266914 | 0.80 | RAB9A (0.47) | CASP3SENP8SENP7SENP6PTGER3 | |
| SCHEMBL7618852 | 0.80 | RARA (0.49) | CASP3SENP8SENP7SENP6RARA | |
| SCHEMBL7623111 | 0.80 | RARA (0.60) | CASP3SENP8SENP7SENP6RARA | |
| SCHEMBL4431905 | 0.78 | KDM4E (0.69) | PTGER3ACMSD | |
| SCHEMBL7617615 | 0.78 | RARA (0.47) | CASP3SENP8SENP7SENP6RARA | |
| Beta-Naphtoic Acid SCHEMBL15940407 | 0.77 | CES2 (0.63) | RARBRARGCTRCACMSDCES2 | |
| SCHEMBL3487237 | 0.77 | KDM5A (0.49) | CASP3SENP8SENP7SENP6RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258811-B1 | ADMINISTERING RETINOIC ACID RECEPTOR AGONIST | EISAI CO., LTD. (JP) | 2001-07-10 | — | — | US | claimed |
| US-6258811-B1 | ADMINISTERING RETINOIC ACID RECEPTOR AGONIST | EISAI CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0930075-A1 | METHODS FOR PREVENTING, INHIBITING OR TREATING GRAFT REJECTION REACTIONS IN GRAFT-VERSUS-HOST DISEASE (GVHD) AND ORGAN TRANSPLANTATION | Eisai Co., Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |