SCHEMBL7943147

SCHEMBL7943147

CCOc1c(CCC(=O)OCCCCO)cc(C)cc1C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 2/20 0.37
CYP4F2 P78329 3/20 0.37
CYP4A11 Q02928 3/20 0.37
F2R P25116 1/20 0.35
POLB P06746 1/20 0.33
ALDH1A1 P00352 1/20 0.33
BRD4 O60885 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8430289 0.97 CYP4F2 (0.38) VCAM1CYP4F2CYP4A11F2RPOLB
SCHEMBL7943173 0.84 CYP4F2 (0.42) VCAM1CYP4F2CYP4A11F2RPOLB
SCHEMBL6567747 0.82 HSPA5 (0.41) VCAM1CYP4F2CYP4A11POLBALDH1A1
SCHEMBL7940366 0.81 VCAM1 (0.41) VCAM1CYP4F2CYP4A11F2RPOLB
SCHEMBL7933544 0.81 RXRA (0.42) VCAM1CYP4F2CYP4A11
SCHEMBL8430359 0.80 HSPA5 (0.36) VCAM1CYP3A4CYP2D6
SCHEMBL7933984 0.80 ALDH1A1 (0.37) VCAM1CYP4F2CYP4A11ALDH1A1CYP2D6
SCHEMBL7933682 0.80 CYP4F2 (0.43) VCAM1CYP4F2CYP4A11F2RPOLB
SCHEMBL7792696 0.80 NPSR1 (0.42) VCAM1
SCHEMBL7944732 0.79 VCAM1 (0.39) VCAM1CYP4F2CYP4A11F2RBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed