SCHEMBL7943803

SCHEMBL7943803

CCCCC(C)C(C)CC(=O)Cl

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 2/20 0.41
CA2 P00918 6/20 0.39
MAPK1 P28482 1/20 0.39
CA1 P00915 5/20 0.38
SLC15A1 P46059 1/20 0.36
FDPS P14324 1/20 0.35
GPR84 Q9NQS5 4/20 0.35
ACE2 Q9BYF1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22500721 0.80 GPR84 (0.50) ALDH1A1TSHRCA2MAPK1GPR84
SCHEMBL1783226 0.80 ALDH1A1 (0.44) ALDH1A1CA2MAPK1CA1SLC15A1
SCHEMBL9176733 0.80 ALDH1A1 (0.46) ALDH1A1TP53TSHRCA2MAPK1
SCHEMBL1410690 0.80 ALDH1A1 (0.46) ALDH1A1TP53TSHRCA2MAPK1
Bicarbonate SCHEMBL6442737 0.79 CA2 (0.52) CA2MAPK1CA1SLC15A1FDPS
SCHEMBL1410252 0.76 ALDH1A1 (0.41) ALDH1A1TP53TSHRCA2MAPK1
SCHEMBL3185161 0.75 DNM1 (0.47) ALDH1A1TSHRCA2MAPK1CA1
SCHEMBL22345156 0.75 DNM1 (0.47) ALDH1A1TSHRCA2MAPK1CA1
SCHEMBL17681357 0.75 ALDH1A1 (0.72) ALDH1A1TP53TSHRMAPK1GPR84
SCHEMBL1410439 0.74 ACE2 (0.52) ALDH1A1TP53TSHRCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001051449-A1 METHOD FOR PRODUCING ENANTIOMER-PURE ANALOGS OF VALPROIC ACID NAU HEINZ (DE) 2001-07-19 WO disclosed